Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Orlando Bus Station | Durham Greyhound Bus Station | Cheapest | ||||
| Bus | Orlando Bus Station | Durham Greyhound Bus Station | Fastest | ||||
| Bus | Orlando Bus Station | Durham Greyhound Bus Station | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Orlando Bus Station | Durham Greyhound Bus Station | No tags | ||||
 | Bus | Orlando Bus Station | Durham Greyhound Bus Station | No tags |
Last refresh of the prices: Yesterday at 8:32 AM EST.
Compare 2 ways to go from Orlando to Durham
Among the sustainable travel choices, the train stands out as a good way to reach Durham. The journey takes about 15 hours 40 minutes, and with fares starting at just $96, it presents an excellent value for a comfortable ride.
Where are the popular stops in Orlando and Durham?
Stops in Orlando
- A555 N John Young Pkwy, Orlando, FL 32805
- BRedCoach Station, 1777 McCoy Road, Orlando, FL 32809
- CJet Set Express Terminal, 3718 LB Mcleod Rd., 32805 Orlando, FL,, United States
- D
Disney World
Disney's All-Star Sports Resort, 1701 West Buena Vista Dr., Orlando, FL 32830 - E
International Dr SuperTours Terminal
5419 International Dr, Orlando, FL 32819, USA - F
Seaworld Hotels
10100 International Drive , Orlando, 32821
Stops in Durham
- A515 W Pettigrew St , Durham, NC 27703
- B
Compare Foods Durham
2000-2004 NC-55, Durham, NC 27704, USA - C
Durham Compare Foods Durham
2000 Avondale Dr, Durham, NC 27704, USA - D
Durham, NC
E Main St at Roxboro St (WB), Durham, NC 27701, USA
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Frequently asked questions about travelling from Orlando to Durham, NC, US by bus
How far is Orlando from Durham?
The distance between Orlando and Durham is approximately 863 km (535 miles).
What are the departure and arrival locations for buses traveling from Orlando to Durham?
Buses departing from Orlando Bus Station in Orlando will take you to Durham Greyhound Bus Station in Durham.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Orlando to Durham, NC, US was searched and found on Nov 19, 2025 with a price of $129To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Orlando to Durham, NC, US, as early as possible.
You can expect to pay from $129 to $310 for a bus ticket from Orlando to Durham, NC, US based on the last 2 days. You can expect to find the cheapest price for the trip at $132 which is on 2025-11-23.
Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
