Find coaches from Panama City, US to Chicago

Previously seen journeys

Next departures from Panama City to Chicago on 11 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound
Panama City Beach Station
Chicago 95Th & Dan RyanNo tags
Greyhound
Panama City Beach Station
537-517 W. Jackson BlvdNo tags
Greyhound
Panama City Beach Station
537-517 W. Jackson BlvdNo tags
FlixBus + Greyhound
Panama City Beach Station
Downtown Greyhound StationNo tags
FlixBus + Greyhound
Panama City Beach Station
Chicago 95Th & Dan RyanNo tags

Accepted payments

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  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus Panama City, US to Chicago: Trip Overview

Average ticket priceUS$164
Average bus trip duration1d 6h
Number of daily buses9
Earliest bus departure07:30
Distance813 miles
Latest bus departure21:10

Panama City to Chicago Bus

Busbud helps you find a bus from Panama City to Chicago. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from Panama City to Chicago.

Discover how much the bus trip from Panama City to Chicago will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Panama City, US - Chicago

  1. How far is Chicago from Panama City by coach?

    The distance between Panama City and Chicago by coach is approximately 815 miles (1314 km).

  2. What is the best way to go from Panama City to Chicago without flying?

    You have the option to select the coach for your journey on this route. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09/10
No data
10/10
US$229
Today
No data
12/10
No data
13/10
No data
14/10
No data
15/10
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16/10
No data
busbud logoThe cheapest trip from Panama City, US to Chicago was searched and found on 10 Oct 2025 with a price of US$229

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Panama City, US to Chicago as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Panama City and Chicago!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Panama City to Chicago.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Panama City to Chicago will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Panama City to Chicago.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

Will you be returning to Panama City, US by bus?

Bus from Chicago to Panama City, US

Why choose Busbud?

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