Find coaches from Panama City, US to Jacksonville, FL

Next departures

Next departures from Panama City to Jacksonville on 13 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.
Panama City Beach Station
Jacksonville Bus StationCheapestFastest

Last refresh of the prices: 05/10/2025 CDT.

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Bus Panama City, US to Jacksonville, FL: Trip Overview

Average ticket priceUS$51
Average bus trip duration6h 45m
Number of daily buses1
Earliest bus departure07:30
Distance245 miles
Latest bus departure12:50

Panama City to Jacksonville Bus

With Busbud, comparing and booking tickets for a bus from Panama City to Jacksonville is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from Panama City to Jacksonville will be provided by the most trusted bus companies.

Discover how much the bus trip from Panama City to Jacksonville will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Panama City, US - Jacksonville, FL

  1. How far is Jacksonville from Panama City by coach?

    The distance between Panama City and Jacksonville by coach is approximately 240 miles (387 km).

  2. What is the best way to go from Panama City to Jacksonville without a car?

    You can travel to Jacksonville from Panama City by coach, which provides a smooth ride and an affordable and convenient trip. You can also consider rideshare services depending on your preferences.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10/10
US$50
11/10
US$49
Today
US$52
13/10
US$52
14/10
US$49
15/10
US$46
16/10
No data
17/10
US$45
busbud logoThe cheapest trip from Panama City, US to Jacksonville, FL was searched and found on 17 Oct 2025 with a price of US$45

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Panama City, US to Jacksonville, FL as early as possible.

You can expect to pay from US$45 to US$52 for a bus ticket from Panama City, US to Jacksonville, FL based on the last 2 days. You can expect to find the cheapest price for the trip at US$45, which is on 2025-10-17.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Panama City to Jacksonville.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from Panama City to Jacksonville, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Panama City to Jacksonville will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Panama City to Jacksonville.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Will you be returning to Panama City, US by bus?

Bus from Jacksonville, FL to Panama City, US

Why choose Busbud?

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