Find coaches from Philadelphia, PA to St. Louis

Find affordable coach tickets from Philadelphia, PA to St. Louis with flexible options. Book your journey now

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Today15 Jul
from US$121
Tomorrow16 Jul
Thu17 Jul
from US$108
Fri18 Jul
Sat19 Jul
Sun20 Jul
Mon21 Jul
from US$111
Tue22 Jul

Cheap buses leaving Thursday

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: 17 July at
    Departure city: Philadelphia
    Departure location: 199 Spring Garden St.
    Arrival time: 17 July at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 17 July at
    Departure city: Philadelphia
    Departure location: 199 Spring Garden St.
    Arrival time: 18 July at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 17 July at
    Departure city: Philadelphia
    Departure location: Philadelphia, 199 Spring Garden St
    Arrival time: 18 July at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 17 July at
    Departure city: Philadelphia
    Departure location: Philadelphia, 199 Spring Garden St
    Arrival time: 18 July at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: 17 July at
    Departure city: Philadelphia
    Departure location: 199 Spring Garden St.
    Arrival time: 18 July at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Compare 2 ways to travel from Philadelphia to St. Louis

Bus
Average priceUS$96 - US$355Average duration1d 4h
33kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average priceUS$133 - US$1,663Average duration1d 7h
118kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Philadelphia to St. Louis

Among the sustainable travel choices, the bus stands out as a good way to reach St. Louis. The journey takes about 1 day, 4 hours 5 minutes and with fares starting at just US$96, it presents an excellent value for a comfortable ride.

15bus per day
1d 4hAverage duration
US$96Cheapest ticket
33kgCO₂ emissions

Bus Philadelphia to St. Louis: Trip Overview

Average ticket priceUS$141
Average bus trip duration1d 4h
Number of daily buses15
Earliest bus departure03:10
Distance808 miles
Latest bus departure20:45

Philadelphia to St. Louis Bus

Busbud helps you find a bus from Philadelphia to St. Louis. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from Philadelphia to St. Louis will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to St. Louis from Philadelphia, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Philadelphia, PA - St. Louis

  1. What's the distance between Philadelphia and St. Louis by coach?

    The distance between Philadelphia and St. Louis by coach is approximately 808 miles (1303 km).

  2. How can I travel from Philadelphia to St. Louis avoiding air travel?

    You have the option to select the coach for your journey on this route. The coach ensures a pleasant travel experience, granting you the opportunity to appreciate the scenery as you make your way to your final stop. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
13/07
US$140
14/07
US$187
Today
US$113
16/07
No data
17/07
US$100
18/07
US$102
19/07
No data
20/07
US$117
busbud logoThe cheapest trip from Philadelphia to St. Louis was searched and found on 17 Jul 2025 with a price of US$100

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Philadelphia to St. Louis as early as possible.

You can expect to pay from US$100 to US$258 for a bus ticket from Philadelphia to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at US$100, which is on 2025-07-17.

Usually FlixBus Inc., Greyhound Lines, Inc. will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Philadelphia and St. Louis!

Much more than a mere vehicle taking you from Philadelphia to St. Louis, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Philadelphia to St. Louis.

Tune out to the fine sounds of your best music playlist on your bus trip from Philadelphia to St. Louis while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

What's the cheapest way to go from Philadelphia to St. Louis?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Philadelphia by bus?

Bus from Philadelphia to St. Louis

You can also go to St. Louis by train

Train from Philadelphia, PA to St. Louis

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

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