Bus Tickets from Philadelphia, PA to St. Louis

Next departures

Next departures for Philadelphia to St. Louis on October 9
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.
199 Spring Garden St.
Gateway StationCheapest
Greyhound Lines, Inc.
199 Spring Garden St.
Gateway StationFastest
Greyhound Lines, Inc.
199 Spring Garden St.
Gateway StationNo tags
FlixBus + Greyhound Lines, Inc.
Philadelphia, 199 Spring Garden St
Gateway StationNo tags
Greyhound Lines, Inc.
199 Spring Garden St.
Gateway StationNo tags

Last refresh of the prices: Yesterday at 1:18 AM EDT.

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Compare 2 ways to go from Philadelphia to St. Louis

Bus
Average PriceUS$67 - US$314Average Duration1d 4h
33kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average PriceUS$139 - US$937Average Duration1d 11h
118kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Philadelphia to St. Louis

Among the sustainable travel choices, the bus stands out as a good way to reach St. Louis. The journey takes about 1 day, 4 hours 25 minutes, and with fares starting at just US$67, it presents an excellent value for a comfortable ride.

20bus per day
1d 4hAverage Duration
US$67Cheapest ticket
33kgCO₂ emissions

Bus Philadelphia, PA to St. Louis: Trip Overview

Average Ticket PriceUS$108
Average Bus Trip Duration1d 4h
Number of daily buses20
Earliest bus departure3:10am
Distance1303 km
Latest bus departure11:15pm

Philadelphia to St. Louis Bus

Busbud helps you find a bus from Philadelphia to St. Louis. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from Philadelphia to St. Louis will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to St. Louis from Philadelphia, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Philadelphia, PA - St. Louis

  1. How far is Philadelphia from St. Louis?

    The distance covered from Philadelphia to St. Louis is 1303 km (808 miles).

  2. What are the departure and arrival locations for buses traveling from Philadelphia to St. Louis?

    Buses traveling this route start their trip at Philadelphia Airport, in Philadelphia, and end it at Gateway Station, in St. Louis.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10-06
US$70
10-07
No data
Today
US$110
10-09
US$124
10-10
US$89
10-11
US$80
10-12
No data
10-13
No data
busbud logoThe cheapest trip from Philadelphia, PA to St. Louis was searched and found on Oct 6, 2025 with a price of US$70

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Philadelphia, PA to St. Louis, as early as possible.

You can expect to pay from US$70 to US$249 for a bus ticket from Philadelphia, PA to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at US$80 which is on 2025-10-11.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Philadelphia and St. Louis!

Much more than a mere vehicle taking you from Philadelphia to St. Louis, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Philadelphia to St. Louis.

Tune out to the fine sounds of your best music playlist on your bus trip from Philadelphia to St. Louis while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

What's the cheapest way to go from Philadelphia, PA to St. Louis?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Philadelphia, PA by bus?

Bus from St. Louis to Philadelphia, PA

You can also go to St. Louis by train

Train from Philadelphia, PA to St. Louis

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

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