Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Nicholson Ave | Santa Fe Depot | Cheapest | |||||
| Nicholson Ave | Old Town San Diego | Fastest | |||||
| Nicholson Ave | Santa Fe Depot | No tags | |||||
| Nicholson Ave | Santa Fe Depot | No tags | |||||
| Nicholson Ave | Santa Fe Depot | No tags |
Last refresh of the prices: Last Sunday at 15:11 PST.
Get from Santa Maria to San Diego
The journey takes about 8 hours 55 minutes, and with fares starting at just £63, it presents an excellent value for a comfortable ride.
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Frequently asked questions about travelling by bus from Santa Maria, US to San Diego, CA, US
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Santa Maria to San Diego?
The cheapest coach tickets from Santa Maria to San Diego start from £63. The average price for this route is around £63. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Santa Maria to San Diego?
The average bus journey time from Santa Maria to San Diego is 8h 55m, covering a distance of 242 miles. The fastest bus can take you there in 8h 13m and is operated by Amtrak.
Which bus companies service the Santa Maria to San Diego route?
What is the earliest and latest departure time for the bus from Santa Maria to San Diego?
The earliest bus departs from Santa Maria to San Diego at 20:05. And the latest bus departs at 20:30.
What are the CO₂ emissions for the bus trip from Santa Maria to San Diego?
A bus journey from Santa Maria to San Diego produces an estimated 10 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Which is the best bus company from Santa Maria to San Diego?
According to Busbud customers, the highest-rated bus company on this route is Amtrak, with an average rating of 4.1 out of 5 stars based on 5627 reviews.
Which company has the best Wi-Fi from Santa Maria to San Diego?
Based on Busbud reviews, the bus company Amtrak has the best Wi-Fi rating with a score of 3.6.
Which bus company offers the most punctual service from Santa Maria to San Diego?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Santa Maria to San Diego?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Amtrak, with a cleanliness rating of 4.5 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Santa Maria, US to San Diego, CA, US was searched and found on 10 Dec 2025 with a price of £60To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santa Maria, US to San Diego, CA, US as early as possible.
You can expect to pay from £60 to £76 for a bus ticket from Santa Maria, US to San Diego, CA, US based on the last 2 days. You can expect to find the cheapest price for the trip at £60, which is on 2025-12-10.
