Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Tampa Bus Station | 4565 Gaynor Ave, North Charleston | Cheapest | |||||
 | Union Station | Charleston Station | Fastest | |||||
FlixBus + Greyhound Lines, Inc. | University of South Florida | 4565 Gaynor Ave, North Charleston | No tags |
Last refresh of the prices: Yesterday at 11:32 EST.
Compare 2 ways to travel from Tampa to Charleston
Among the sustainable travel choices, the bus stands out as a good way to reach Charleston. The journey takes about 19 hours 55 minutes and with fares starting at just £48, it presents an excellent value for a comfortable ride.
Where are the popular stops in Tampa and Charleston?
Stops in Tampa
- A
Tampa 13th Avenue Bus Stop (McDonald's)
2101 E 13th Ave (McDonald's), Tampa, FL 33605 - B
Tampa USF, FL
3801 USF Holly Drive, Tampa., FL 33620, USA - C
Greyhound Station
610 E Polk St, Tampa, FL 33602, USA - D
E Sligh Ave
11555 E Sligh Ave, Seffner, FL 33584, USA - E
N Marion St & E Laurel St
551 E Laurel St, Tampa, FL 33602, USA - F
Port of Tampa
200-298 FL-60, Tampa, FL 33602, USA
Stops in Charleston
- A
Charleston Bus Station
3610 Dorchester Rd, North Charleston, SC 29405
Compare bus companies
Frequently asked questions about travelling by bus from Tampa to Charleston, SC, US
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Tampa to Charleston?
The cheapest coach tickets from Tampa to Charleston start from £48. The average price for this route is around £69. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Tampa to Charleston?
The average bus journey time from Tampa to Charleston is 19h 55m, covering a distance of 370 miles. The fastest bus can take you there in 11h and is operated by Amtrak.
Which bus companies service the Tampa to Charleston route?
What is the earliest and latest departure time for the bus from Tampa to Charleston?
The earliest bus departs from Tampa to Charleston at 20:00. And the latest bus departs at 22:35.
What are the CO₂ emissions for the bus trip from Tampa to Charleston?
A bus journey from Tampa to Charleston produces an estimated 15 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Which is the best bus company from Tampa to Charleston?
According to Busbud customers, the highest-rated bus company on this route is Amtrak, with an average rating of 4.1 out of 5 stars based on 5627 reviews.
Which company has the best Wi-Fi from Tampa to Charleston?
Based on Busbud reviews, the bus company Amtrak has the best Wi-Fi rating with a score of 3.6.
Which bus company offers the most punctual service from Tampa to Charleston?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Tampa to Charleston?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Amtrak, with a cleanliness rating of 4.5 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Tampa to Charleston, SC, US was searched and found on 16 Dec 2025 with a price of £51To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Tampa to Charleston, SC, US as early as possible.
You can expect to pay from £51 to £365 for a bus ticket from Tampa to Charleston, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at £51, which is on 2025-12-16.
Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Tampa to Charleston, SC, US?
The bus is the cheapest travel choice for this destination
