What is the distance between Buffalo and Indianapolis?

Buffalo and Indianapolis are 435 miles (701 km) apart.

What are the departure and arrival stations when taking the bus from Buffalo to Indianapolis?

If you're headed to Indianapolis from Buffalo, chances are that your bus will depart from Buffalo Airport and arrive at Greyhound Amtrak Station. These are the main pick-up and drop-off locations on this route, there are other pick-up and drop-off locations that could make it easier for you to reach your destination.

Bus Buffalo to Indianapolis from $69 | Compare & Save up to 38%

Previously seen trips

Next departures for Buffalo to Indianapolis on November 25
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound + FlixBus	Bus	7:55am	Niagara Frontier Transportation Authority	1d	8:00am	Downtown Transit Center	No tags
FlixBus + Greyhound	Bus	7:55am	Niagara Frontier Transportation Authority	1d 6h	2:40pm	Indianapolis Northeast	No tags
Greyhound + FlixBus	Bus	7:50pm	Niagara Frontier Transportation Authority	20h 50m	4:40pm	Indianapolis Bus Station	No tags
FlixBus + Greyhound	Bus	7:50pm	Niagara Frontier Transportation Authority	1d 3h	11:15pm	Downtown Transit Center	No tags
FlixBus + Greyhound	Bus	7:55am	Niagara Frontier Transportation Authority	1d 6h	2:40pm	Indianapolis Northeast	No tags

Compare 2 ways to go from Buffalo to Indianapolis

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach Indianapolis. The journey takes about 19 hours 5 minutes and with fares starting at just $69, it presents an excellent value for a comfortable ride.

1bus per day

19h 5mAverage Duration

434 milesDistance

17kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$69 - $112	Average Duration19h 5m	CO₂ emissions 17kg CO₂e
Train	Average Price$170 - $170	Average Duration23h 10m	CO₂ emissions 65kg CO₂e