Bus Tickets from Des Moines to Cleveland, OH, US

Next departures

Next departures for Des Moines to Cleveland on October 10
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.
Des Moines
Cleveland Bus StationCheapestFastest
Greyhound Lines, Inc. + FlixBus
Des Moines
Cleveland Bus StationNo tags
Greyhound Lines, Inc. + FlixBus
Des Moines
Cleveland Bus StationNo tags

Last refresh of the prices: Last Friday at 11:34 PM CDT.

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Bus Des Moines to Cleveland, OH, US: Trip Overview

Average ticket price$108
Average bus trip duration19h 5m
Number of daily buses1
Earliest bus departure5:30am
Distance615 miles (991 km)
Latest bus departure9:30am

Des Moines to Cleveland Bus

With Busbud, comparing and booking tickets for a bus from Des Moines to Cleveland is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Des Moines to Cleveland from the most reliable bus companies operating this trip.

Discover how much the bus trip from Des Moines to Cleveland will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip Des Moines - Cleveland, OH, US

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10/06
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10/07
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Today
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10/09
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10/10
$100
10/11
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10/12
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10/13
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busbud logoThe cheapest trip from Des Moines to Cleveland, OH, US was searched and found on Oct 10, 2025 with a price of $100

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Des Moines to Cleveland, OH, US, as early as possible.

You can expect to pay from $100 to $100 for a bus ticket from Des Moines to Cleveland, OH, US based on the last 2 days. You can expect to find the cheapest price for the trip at $100 which is on 2025-10-10.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Des Moines to Cleveland.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Des Moines to Cleveland, get comfy and count the stars.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Des Moines to Cleveland will emit less CO2 than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Des Moines to Cleveland.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Will you be returning to Des Moines by bus?

Bus from Cleveland, OH, US to Des Moines

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