- Durham to Knoxville buses
Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound | Bus | Durham Greyhound Bus Station | Knoxville Bus Station | No tags | ||||
Greyhound + FlixBus | Bus | Durham Greyhound Bus Station | Knoxville Bus Station | No tags | ||||
FlixBus + Greyhound | Bus | Durham Greyhound Bus Station | Knoxville Bus Station | No tags | ||||
FlixBus + Greyhound | Bus | Durham Greyhound Bus Station | Knoxville Bus Station | No tags | ||||
Greyhound + FlixBus | Bus | Durham Greyhound Bus Station | Knoxville Bus Station | No tags |
Get from Durham to Knoxville
The journey takes about 13 hours 20 minutes and with fares starting at just $77, it presents an excellent value for a comfortable ride.
Where are the popular stops in Durham and Knoxville?
Stops in Durham
- A515 W Pettigrew St , Durham, NC 27703
- B
Compare Foods Durham
2000-2004 NC-55, Durham, NC 27704, USA - C
Durham Compare Foods Durham
2000 Avondale Dr, Durham, NC 27704, USA - D
Durham, NC
E Main St at Roxboro St (WB), Durham, NC 27701, USA
Stops in Knoxville
- AKnoxville Area Transit Bus Stop, 100 Kirkwood St, Knoxville, TN 37914, USA
Compare bus companies
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Frequently asked questions about traveling from Durham, NC, US to Knoxville, TN by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Durham to Knoxville?
The cheapest bus tickets from Durham to Knoxville start from $77. The average price for this route is around $143. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Durham to Knoxville?
The average bus trip duration from Durham to Knoxville is 13h 20m, covering a distance of 278 miles (448 km). The quickest bus can get you there in 13h 50m and is operated by FlixBus.
Which bus companies service the Durham to Knoxville route?
Several major train operators operate on this route with 1 trains available per day.
What is the earliest and latest departure time for the bus from Durham to Knoxville?
The earliest bus departs from Durham to Knoxville at 8:30am. And the latest bus departs at 8:35am.
What are the CO₂ emissions for the bus trip from Durham to Knoxville?
A bus trip from Durham to Knoxville generates an estimated 11 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.






