Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Bus station | Lowell, MA | CheapestFastest |
Last refresh of the prices: Yesterday at 5:18 PM EDT.
Get from Florence to Lowell
The journey takes about 1 day, 3 hours 15 minutes and with fares starting at just $125, it presents an excellent value for a comfortable ride.
Where are the popular stops in Florence and Lowell?
Stops in Florence
- A619 S Irby St, Florence, SC 29501, USA
- B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA
Stops in Lowell
- A
Regional Transit Center Bus Stop
101 Thorndike St, Lowell, MA 01852
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Florence, SC, US to Lowell by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Florence to Lowell?
The cheapest bus tickets from Florence to Lowell start from $125. The average price for this route is around $125. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Florence to Lowell?
The average bus trip duration from Florence to Lowell is 1d 3h, covering a distance of 740 miles (1193 km). The quickest bus can get you there in 1d 3h and is operated by Greyhound.
Which bus companies service the Florence to Lowell route?
Several major bus companies operate on this route with 1 buses available per day.
What is the earliest and latest departure time for the bus from Florence to Lowell?
The earliest bus departs from Florence to Lowell at 4:30pm. And the latest bus departs at 4:30pm.
What are the CO₂ emissions for the bus trip from Florence to Lowell?
A bus trip from Florence to Lowell generates an estimated 29.809025000000002 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Florence, SC, US to Lowell was searched and found on May 20, 2026 with a price of $117To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Lowell, as early as possible.
You can expect to pay from $117 to $117 for a bus ticket from Florence, SC, US to Lowell based on the last 2 days. You can expect to find the cheapest price for the trip at $117 which is on 2026-05-20.
