Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Florence, SC | Orlando Bus Station | CheapestFastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Bus station | Orlando Bus Station | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Bus station | Orlando Bus Station | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Bus station | Orlando Bus Station | No tags |
Last refresh of the prices: Today at 1:53 PM EDT.
Compare 2 ways to go from Florence to Orlando
Among the sustainable travel choices, the Train stands out as a good way to reach Orlando. The journey takes about 13 hours 17 minutes and with fares starting at just CHF 53, it presents an excellent value for a comfortable ride.
Where are the popular stops in Florence and Orlando?
Stops in Florence
- A
Florence Bus Station
619 S Irby St, Florence, SC 29501, USA - B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA
Stops in Orlando
- A
Orlando Bus Station
555 N John Young Pkwy, Orlando, FL 32805 - B
Orlando RedCoach Station
RedCoach Station, 1777 McCoy Road, Orlando, FL 32809 - C
Jet Set Express Terminal
Jet Set Express Terminal, 3718 LB Mcleod Rd., 32805 Orlando, FL,, United States - D
Disney World
Disney's All-Star Sports Resort, 1701 West Buena Vista Dr., Orlando, FL 32830 - E
International Dr SuperTours Terminal
5419 International Dr, Orlando, FL 32819, USA - F
Seaworld Hotels
10100 International Drive , Orlando, 32821
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Frequently asked questions about traveling from Florence, SC, US to Orlando by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Florence to Orlando?
The cheapest bus tickets from Florence to Orlando start from CHF 49. The average price for this route is around CHF 82. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Florence to Orlando?
The average bus trip duration from Florence to Orlando is 15h 40m, covering a distance of 401 miles (647 km). The quickest bus can get you there in 8h 25m and is operated by FlixBus.
Which bus companies service the Florence to Orlando route?
What is the earliest and latest departure time for the bus from Florence to Orlando?
The earliest bus departs from Florence to Orlando at 12:05am. And the latest bus departs at 4:15pm.
What are the CO₂ emissions for the bus trip from Florence to Orlando?
A bus trip from Florence to Orlando generates an estimated 16.1629 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Florence to Orlando?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 12791 reviews.
Which bus company has the best Wi-Fi from Florence to Orlando?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Florence to Orlando?
According to Busbud traveler reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Florence to Orlando?
According to Busbud traveler reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Florence, SC, US to Orlando was searched and found on Jun 24, 2026 with a price of CHF 50To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Orlando, as early as possible.
You can expect to pay from CHF 50 to CHF 107 for a bus ticket from Florence, SC, US to Orlando based on the last 2 days. You can expect to find the cheapest price for the trip at CHF 50 which is on 2026-06-24.
