Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Frankfurt Hbf | Husova, 2713/60 | Cheapest | ||||
 | Bus | Frankfurt - Main bus station | Plzeň Autobusová Zastávka | Fastest | ||||
| Bus | Frankfurt Hbf | Husova, 2713/60 | No tags | ||||
| Bus | FRA Frankfurt airport | Husova, 2713/60 | No tags | ||||
| Bus | FRA Frankfurt airport | Husova, 2713/60 | No tags |
Last refresh of the prices: Last Saturday at 8:23 PM CET.
Compare 3 ways to go from Frankfurt am Main to Plzeň
Among the sustainable travel choices, the carpool stands out as the good way to reach Plzeň. The journey takes about 4 hours 10 minutes and with fares starting at just $43, it presents an excellent value for a comfortable ride.
Where are the popular stops in Frankfurt am Main and Plzeň?
Stops in Frankfurt am Main
- B
Hbf
Am Hauptbahnhof 8, 60329 Frankfurt am Main, Germany - CHedderichstraße 51, 60594 Frankfurt am Main, Germany
- D
Frankfurt Onibus
Stephanstraße 10, 60547 Frankfurt am Main, Germany - E
Braubachstraße 41
Braubachstraße 41, 60311 Frankfurt am Main, Germany - F
Flughafen Hahn Airport (HHN)
Flugplatz Hahn 850, 55483 Lautzenhausen, Germany
Stops in Plzeň
- AHusova 2713/60, 301 00 Plzeň 3, Czech Republic
- BRokycanská 1171/6, Lobzy 301 00 Plzeň-Plzeň 4, Czech Republic
- C
nám. Republiky 358/33
nám. Republiky 358/33, Vnitřní Město, 301 00 Plzeň-Plzeň 3, Czech Republic - D
Rokycanská 1328/112
Rokycanská 1328/112, Doubravka, 312 00 Plzeň-Plzeň 4, Czech Republic - E
Plzen
Přeštická 1761/4, Jižní Předměstí, 301 00 Plzeň-Plzeň 3, Czechia
Compare bus companies
Frequently asked questions about traveling from Frankfurt am Main to Plzeň by bus
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Frankfurt am Main to Plzeň was searched and found on Nov 27, 2025 with a price of $24To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Frankfurt am Main to Plzeň, as early as possible.
You can expect to pay from $24 to $62 for a bus ticket from Frankfurt am Main to Plzeň based on the last 2 days. You can expect to find the cheapest price for the trip at $24 which is on 2025-11-27.
Usually RegioJet will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Frankfurt am Main to Plzeň?
The bus is the cheapest travel choice for this destinationTop traveled bus routes
People from around the world trust Busbud
Popular bus departures from Frankfurt am Main
- Find bus tickets from Frankfurt am Main to Stuttgart
- Frankfurt am Main to Amsterdam bus times and fares
- How to travel from Frankfurt am Main to Paris
- Find bus tickets from Frankfurt am Main to Munich
- Frankfurt am Main to Hamburg bus times and fares
- How to travel from Frankfurt am Main to Berlin
- Find bus tickets from Frankfurt am Main to Cologne