- Frederick to Syracuse buses
Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
![]() | Bus | Frederick | Syracuse (Regional Transportation Center) | No tags | ||||
Greyhound + FlixBus | Bus | Frederick | Syracuse (Regional Transportation Center) | No tags | ||||
![]() | Bus | Frederick | Syracuse (Regional Transportation Center) | No tags | ||||
Greyhound + FlixBus | Bus | Frederick | Syracuse (Regional Transportation Center) | No tags | ||||
FlixBus + Greyhound | Bus | Frederick | Syracuse (Regional Transportation Center) | No tags |
Get from Frederick to Syracuse
The journey takes about 13 hours 15 minutes and with fares starting at just $115, it presents an excellent value for a comfortable ride.
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Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Frederick to Syracuse, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Frederick to Syracuse?
The cheapest bus tickets from Frederick to Syracuse start from $115. The average price for this route is around $115. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Frederick to Syracuse?
The average bus trip duration from Frederick to Syracuse is 13h 15m, covering a distance of 261 miles (421 km). The quickest bus can get you there in 13h 15m and is operated by Greyhound.
Which bus companies service the Frederick to Syracuse route?
Several major train operators operate on this route with 2 trains available per day.
What is the earliest and latest departure time for the bus from Frederick to Syracuse?
The earliest bus departs from Frederick to Syracuse at 12:30am. And the latest bus departs at 6:35pm.
What are the CO₂ emissions for the bus trip from Frederick to Syracuse?
A bus trip from Frederick to Syracuse generates an estimated 11 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.






