Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Greensburg (Westmoreland Transit Center) | Downtown Greyhound Station | Cheapest | ||||
| Bus | Greensburg (Westmoreland Transit Center) | 537-517 W. Jackson Blvd | Fastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Greensburg (Westmoreland Transit Center) | Chicago 95Th & Dan Ryan | No tags |
Last refresh of the prices: Yesterday at 8:45 AM EST.
Compare 2 ways to go from Greensburg to Chicago
Among the sustainable travel choices, the bus stands out as the good way to reach Chicago. The journey takes about 13 hours 55 minutes and with fares starting at just $82, it presents an excellent value for a comfortable ride.
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Greensburg, PA to Chicago by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Greensburg to Chicago?
The cheapest bus tickets from Greensburg to Chicago start from $82. The average price for this route is around $83. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Greensburg to Chicago?
The average bus trip duration from Greensburg to Chicago is 13h 55m, covering a distance of 432 miles (696 km). The quickest bus can get you there in 15h 45m and is operated by Greyhound.
Which bus companies service the Greensburg to Chicago route?
Several major train operators operate on this route with 3 trains available per day.
What is the earliest and latest departure time for the bus from Greensburg to Chicago?
The earliest bus departs from Greensburg to Chicago at 10:10am. And the latest bus departs at 5:15pm.
What are the CO₂ emissions for the bus trip from Greensburg to Chicago?
A bus trip from Greensburg to Chicago generates an estimated 17 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Greensburg, PA to Chicago was searched and found on Jan 4, 2026 with a price of $79To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greensburg, PA to Chicago, as early as possible.
What's the cheapest way to go from Greensburg, PA to Chicago?
The bus is the cheapest travel choice for this destination
