Next departures for Grenoble to Brussels on November 22
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Bus
Gare de Grenoble
Brussels-South (Gare du Midi)
CheapestFastest
Next departures for Grenoble to Brussels on November 23
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Bus
Gare de Grenoble
Brussels-South (Gare du Midi)
CheapestFastest
Bus
Gare de Grenoble
Brussels-South (Gare du Midi)
No tags
Next departures for Grenoble to Brussels on November 24
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Bus
Gare de Grenoble
Brussels-South (Gare du Midi)
Cheapest
Bus
Gare de Grenoble
Brussels-South (Gare du Midi)
Fastest
Next departures for Grenoble to Brussels on November 25
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Bus
Gare de Grenoble
Brussels-South (Gare du Midi)
CheapestFastest
Next departures for Grenoble to Brussels on November 26
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Bus
Gare de Grenoble
Brussels-South (Gare du Midi)
CheapestFastest
Next departures for Grenoble to Brussels on November 27
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Bus
Gare de Grenoble
Brussels-South (Gare du Midi)
CheapestFastest
Bus
Gare de Grenoble
Brussels-South (Gare du Midi)
No tags
Last refresh of the prices: Today at 12:39 AM CET.
Compare 3 ways to go from Grenoble to Brussels
We recommend carpooling
Among the sustainable travel choices, the carpool stands out as the good way to reach Brussels. The journey takes about 8 hours 50 minutes and with fares starting at just $51, it presents an excellent value for a comfortable ride.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Based on 11145 reviews, the company was rated 3.7 stars on Busbud. Travelers were especially satisfied with the ticket access and the staff but often complained with the wifi. BlaBlaCar Bus ticket prices on this trip start at $33
Frequently asked questions about traveling from Grenoble to Brussels by bus
What is the distance between Grenoble and Brussels?
The distance separating Grenoble and Brussels is 398 miles (641 km).
What are the departure and arrival stations when taking the bus from Grenoble to Brussels?
If you're headed to Brussels from Grenoble, chances are that your bus will leave from Condillac-Universités and arrive at Brussels South (Gare du Midi). These are the primary departure and arrival locations on this route, but you can find others that could fit better into your travel plans.
What are the best sights and things to do in Brussels?
Once in Brussels, you can start exploring the city and discover its surroundings. The top sights and things to do are Fête de la BD - Comic Festival in Brussels! Brussels design market, Couleur Café Music Festival, Visit the Laeken Royal Greenhouses in Brussels and 20km of Brussels - 36 years of Brussels' most popular race.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/20
$71
11/21
$107
Today
$59
11/23
$71
11/24
$42
11/25
$52
11/26
$44
11/27
$44
The cheapest trip from Grenoble to Brussels was searched and found on Nov 24, 2025 with a price of $42
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Grenoble to Brussels, as early as possible.
You can expect to pay from $42 to $124 for a bus ticket from Grenoble to Brussels based on the last 2 days. You can expect to find the cheapest price for the trip at $42 which is on 2025-11-24.
What's the cheapest way to go from Grenoble to Brussels?
The bus is the cheapest travel choice for this destination
The cheapest trip from Grenoble to Brussels was searched and found on Nov 24, 2025 with a price of $42
The bus is the cheapest travel choice for this destination
