Next departures for Karlsruhe to Milano on November 21
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Südseite Hauptbahnhof
Lampugnano bus station
CheapestFastest
Südseite Hauptbahnhof
Milan (Malpensa Aeroporto Terminal 1)
No tags
Flixtrain + Flixbus
Karlsruhe Hbf
Milan (Malpensa Aeroporto Terminal 1)
No tags
Karlsruhe
Lampugnano
No tags
Südseite Hauptbahnhof
Milan (Malpensa Aeroporto Terminal 1)
No tags
Next departures for Karlsruhe to Milano on November 23
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Südseite Hauptbahnhof
Lampugnano bus station
Cheapest
Südseite Hauptbahnhof
Lampugnano bus station
Fastest
Südseite Hauptbahnhof
Milan (Malpensa Aeroporto Terminal 1)
No tags
Flixtrain + Flixbus
Karlsruhe Hbf
Milan (Malpensa Aeroporto Terminal 1)
No tags
Karlsruhe
Lampugnano
No tags
Next departures for Karlsruhe to Milano on November 24
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Karlsruhe
Lampugnano
CheapestFastest
Last refresh of the prices: Yesterday at 6:11 PM CET.
Compare 3 ways to go from Karlsruhe to Milano
We recommend carpooling
Among the sustainable travel choices, the carpool stands out as the good way to reach Milano. The journey takes about 5 hours 50 minutes and with fares starting at just $36, it presents an excellent value for a comfortable ride.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Based on 11143 reviews, the company was rated 3.7 stars on Busbud. Travelers were especially satisfied with the ticket access and the staff but often complained with the wifi. BlaBlaCar Bus ticket prices on this trip start at $42
Based on 893 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the staff and the temperature but often complained with the wifi. MarinoBus ticket prices on this trip start at $41
Frequently asked questions about traveling from Karlsruhe to Milano by bus
What is the distance between Karlsruhe and Milano?
About 248 miles (399 km) separate Karlsruhe and Milano.
What are the departure and arrival stations when taking the bus from Karlsruhe to Milano?
If you're headed to Milano from Karlsruhe, chances are that your bus will leave from Südseite Hauptbahnhof and arrive at Lampugnano. These are the main pick-up and drop-off locations on this route, but you can also find other options that could better fit your plans.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/19
$33
11/20
$34
Today
$34
11/22
$31
11/23
$37
11/24
$83
11/25
$31
11/26
$31
The cheapest trip from Karlsruhe to Milano was searched and found on Nov 25, 2025 with a price of $31
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Karlsruhe to Milano, as early as possible.
You can expect to pay from $31 to $107 for a bus ticket from Karlsruhe to Milano based on the last 2 days. You can expect to find the cheapest price for the trip at $31 which is on 2025-11-25.
Usually BlaBlaCar Bus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.