Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound | Knoxville Bus Station | 4565 Gaynor Ave, North Charleston | No tags | |||||
Greyhound + FlixBus | 100 Kirkwood St | 4565 Gaynor Ave, North Charleston | No tags | |||||
FlixBus + Greyhound | 100 Kirkwood St | 4565 Gaynor Ave, North Charleston | No tags | |||||
Greyhound + FlixBus | 100 Kirkwood St | 4565 Gaynor Ave, North Charleston | No tags | |||||
Greyhound + FlixBus | Knoxville Bus Station | 4565 Gaynor Ave, North Charleston | No tags |
Accepted payments
Get from Knoxville to Charleston
The journey takes about 19 hours 40 minutes and with fares starting at just $100, it presents an excellent value for a comfortable ride.
Bus Knoxville, TN to Charleston, SC, US: Trip Overview
Knoxville to Charleston Bus
With Busbud, comparing and booking tickets for a bus from Knoxville to Charleston is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
Bus service from Knoxville to Charleston will be provided by the most trusted bus companies.
From cheap bus tickets to more luxurious buses traveling from Knoxville to Charleston, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in Knoxville and Charleston?
Frequently asked questions for your trip Knoxville, TN - Charleston, SC, US
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while traveling from Knoxville to Charleston.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
Much more than a mere vehicle taking you from Knoxville to Charleston, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Knoxville to Charleston that are otherwise impossible to come by with a plane.
Tune out to the fine sounds of your best music playlist on your bus trip from Knoxville to Charleston while indulging in miles on end of beautiful scenic views.
Did you know?
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
Top traveled bus routes
Why choose Busbud?
The Best Way To Book Bus and Train Tickets
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Popular Buses Connecting Knoxville
Buses Leaving from Knoxville
- Bus from Knoxville to Charlotte
- Bus Knoxville - Marathon
- Knoxville - Lexington
- Bus from Knoxville to Orlando
- Bus Knoxville - Chicago
- Knoxville - Miami
- Bus from Knoxville to Nashville
- Bus Knoxville - Atlanta
- Knoxville - New York City
- Bus from Knoxville to Memphis
- Bus Knoxville - Washington
- Knoxville - Tampa
- Bus from Knoxville to Jackson
- Bus Knoxville - Cincinnati
Buses Going to Knoxville
- Bus from Nashville to Knoxville
- Bus Memphis - Knoxville
- Charlotte - Knoxville
- Bus from Chicago to Knoxville
- Bus Tampa - Knoxville
- Detroit - Knoxville
- Bus from Atlanta to Knoxville
- Bus Hartford - Knoxville
- New York City - Knoxville
- Bus from Louisville to Knoxville
- Bus Cincinnati - Knoxville
- Lexington - Knoxville
- Bus from Greenville to Knoxville
- Bus Dallas - Knoxville
- Cookeville - Knoxville
Popular Buses Connecting Charleston
Buses Leaving from Charleston
- Bus from Charleston to Baltimore
- Bus Charleston - Atlanta
- Charleston - Tulsa
- Bus from Charleston to Fort Worth
- Bus Charleston - Miami
- Charleston - Jacksonville
- Bus from Charleston to Savannah
- Bus Charleston - Greenville
- Charleston - Charlotte
- Bus from Charleston to Orlando
- Bus Charleston - New York City
- Charleston - Raleigh
- Bus from Charleston to Florence
- Bus Charleston - Greensboro
- Charleston - Washington
Buses Going to Charleston
- Bus from Myrtle Beach to Charleston
- Bus Baltimore - Charleston
- Boston - Charleston
- Bus from Greenville to Charleston
- Bus Nashville - Charleston
- Raleigh - Charleston
- Bus from Savannah to Charleston
- Bus Atlanta - Charleston
- Orlando - Charleston
- Bus from New York City to Charleston
- Bus Charlotte - Charleston
- Miami - Charleston
- Bus from Jacksonville to Charleston
- Bus Tampa - Charleston
- Newark - Charleston
Popular routes in this country
- Bus from Fort Lauderdale to Orlando
- Bus Dallas - Houston
- Albany - New York City
- Bus from Las Vegas to Los Angeles
- Bus Tampa - Miami
- Austin - Dallas
- Bus from Dallas to Austin
- Bus Seattle - Leavenworth
- Miami - Tampa
- Bus from Austin to Houston
- Bus Houston - San Antonio
- Houston - Austin
- Bus from San Antonio to Houston
- Bus Atlanta - Orlando
- Dallas - San Antonio