Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Price and booking link |
|---|---|---|---|---|---|---|---|
 | Bus | Knoxville Bus Station | Columbus (E Mound St) | ||||
| Bus | Knoxville Bus Station | Columbus (E Mound St) | ||||
| Bus | Knoxville Bus Station | Columbus (E Mound St) | ||||
| Bus | 100 Kirkwood St | Columbus (E Mound St) | ||||
| Bus | Knoxville Bus Station | Columbus (E Mound St) |
Get from Knoxville to Columbus
The journey takes about 9 hours 40 minutes and with fares starting at just $94, it presents an excellent value for a comfortable ride.
Where are the popular stops in Knoxville and Columbus?
Stops in Knoxville
- A
100 Kirkwood St
Knoxville Area Transit Bus Stop, 100 Kirkwood St, Knoxville, TN 37914, USA
Stops in Columbus
- A
Columbus Bus Station
25 E Rich St, Columbus, OH 43205, USA
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Greyhound Knoxville Columbus recent customer reviews
Its honestly really scary and id never do it again as a young girl alone
Elle R.
Frequently asked questions about traveling from Knoxville, TN to Columbus, OH by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Knoxville to Columbus?
The cheapest bus tickets from Knoxville to Columbus start from $94. The average price for this route is around $118. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Knoxville to Columbus?
The average bus trip duration from Knoxville to Columbus is 9h 40m, covering a distance of 278 miles (447 km). The quickest bus can get you there in 9h 40m and is operated by Greyhound.
Which bus companies service the Knoxville to Columbus route?
Several major bus companies operate on this route with 1 buses available per day.
What is the earliest and latest departure time for the bus from Knoxville to Columbus?
The earliest bus departs from Knoxville to Columbus at 6:10pm. And the latest bus departs at 10:00pm.
What are the CO₂ emissions for the bus trip from Knoxville to Columbus?
A bus trip from Knoxville to Columbus generates an estimated 11.171149999999999 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Knoxville, TN to Columbus, OH was searched and found on Jun 14, 2026 with a price of $109To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Knoxville, TN to Columbus, OH, as early as possible.
