Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Knoxville Bus Station | Jackson (Union Station) | CheapestFastest |
Last refresh of the prices: Last Wednesday at 11:36 AM EST.
Get from Knoxville to Jackson
The journey takes about 13 hours 10 minutes and with fares starting at just $247, it presents an excellent value for a comfortable ride.
Where are the popular stops in Knoxville and Jackson?
Stops in Knoxville
- AKnoxville Area Transit Bus Stop, 100 Kirkwood St, Knoxville, TN 37914, USA
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Knoxville, TN to Jackson, MS, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Knoxville to Jackson?
The cheapest bus tickets from Knoxville to Jackson start from $247. The average price for this route is around $247. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Knoxville to Jackson?
The average bus trip duration from Knoxville to Jackson is 13h 10m, covering a distance of 442 miles (712 km). The quickest bus can get you there in 13h 10m and is operated by Greyhound.
Which bus companies service the Knoxville to Jackson route?
Several major train operators operate on this route with 1 trains available per day.
What is the earliest and latest departure time for the bus from Knoxville to Jackson?
The earliest bus departs from Knoxville to Jackson at 7:05pm. And the latest bus departs at 7:05pm.
What are the CO₂ emissions for the bus trip from Knoxville to Jackson?
A bus trip from Knoxville to Jackson generates an estimated 18 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Knoxville, TN to Jackson, MS, US was searched and found on Jan 19, 2026 with a price of $128To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Knoxville, TN to Jackson, MS, US, as early as possible.
You can expect to pay from $128 to $178 for a bus ticket from Knoxville, TN to Jackson, MS, US based on the last 2 days. You can expect to find the cheapest price for the trip at $128 which is on 2026-01-19.
