What is the travel distance from Knoxville to Myrtle Beach?

The distance separating Knoxville and Myrtle Beach is 326 miles (525 km).

What are the departure and arrival stations when taking the bus from Knoxville to Myrtle Beach?

Buses going from Knoxville to Myrtle Beach start their journey at 100 Kirkwood St and reach their destination at Bus Station.

What are the best sights and things to do in Myrtle Beach?

Once in Myrtle Beach, you can start exploring the city and discover its surroundings. The top sights and things to do are Myrtle Beach Golf, Wild Water and Wheels, Captain Hook's Adventure Golf, Wonderworks and Ripley's Myrtle Beach Aquarium.

Bus Knoxville to Myrtle Beach from $177 | Refundable Tickets

Previously seen trips

Next departures for Knoxville to Myrtle Beach on November 11
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	1:55am	Knoxville Bus Station	16h 15m	5:10pm	Bus Station	No tags
Bus	2:55am	Knoxville Bus Station	14h 15m	5:10pm	Bus Station	No tags
Bus	7:20pm	Knoxville Bus Station	21h 50m	5:10pm	Bus Station	No tags
Bus	7:25pm	Knoxville Bus Station	21h 45m	5:10pm	Bus Station	No tags
Bus	7:25pm	Knoxville Bus Station	21h 45m	5:10pm	Bus Station	No tags

Get from Knoxville to Myrtle Beach

This route is served by bus only

The journey takes about 21 hours 45 minutes and with fares starting at just $177, it presents an excellent value for a comfortable ride.

1bus per day

21h 45mAverage Duration

325 milesDistance

13kgCO₂ emissions

Compare bus companies

Greyhound

3.5/587,367 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Where are the popular stops in Knoxville and Myrtle Beach?

Stops in Knoxville

A - 100 Kirkwood St

Stops in Myrtle Beach

A - Bus Station

Frequently asked questions about traveling from Knoxville, TN to Myrtle Beach by bus

What is the travel distance from Knoxville to Myrtle Beach?
What are the departure and arrival stations when taking the bus from Knoxville to Myrtle Beach?
What are the best sights and things to do in Myrtle Beach?