Compare 2 ways to go from Mainz to Rome.
Busbud recommends taking the bus from Mainz to RomeAmong the sustainable travel choices, the bus stands out as the good way to reach Rome. The journey takes about 1 day, 2 hours 25 minutes and with fares starting at just $102, it presents an excellent value for a comfortable ride.
Bus Mainz to Rome: Trip Overview
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Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Mainz to Rome Bus
Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Mainz to Rome.
We make sure you can find a bus service from Mainz to Rome from the most reliable bus companies operating this trip.
Whether it is cheap bus tickets or more luxurious buses going to Rome from Mainz, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in Mainz and Rome?
Frequently asked questions for your trip Mainz - Rome
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Mainz to Rome was searched and found on May 18, 2025 with a price of $69To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mainz to Rome, as early as possible.
You can expect to pay from $69 to $159 for a bus ticket from Mainz to Rome based on the last 2 days. You can expect to find the cheapest price for the trip at $69 which is on 2025-05-18.
About Bus Travel
Bus Travel Tips
If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Mainz to Rome but it'll also be endearing to native speakers who will surely appreciate your effort.
Start sightseeing the minute your bus leaves the station. If you're on the night bus from Mainz to Rome, get comfy and count the stars.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Mainz to Rome.
Make a music playlist for your bus ride from Mainz to Rome, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
9.2% of ground transportation in Europe is done by bus versus 7.4% by train.
What's the cheapest way to go from Mainz to Rome?
The bus is the cheapest travel choice for this destinationTop traveled bus routes
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Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. Use Busbud to book your trip online, in your own language and currency, wherever you are. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.