Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Messina Centrale | Rome Tiburtina Bus Station | Cheapest | ||||
 | Bus | Piazza della Repubblica | Tiburtina | Fastest | ||||
| Bus | Messina Centrale | Rome Tiburtina Bus Station | No tags | ||||
 | Bus | Messina Centrale | Rome Tiburtina Bus Station | No tags | ||||
| Bus | Messina Centrale | Rome Tiburtina Bus Station | No tags |
Last refresh of the prices: Today at 3:59 PM CEST.
Compare 2 ways to go from Messina to Rome
Among the sustainable travel choices, the Bus stands out as a good way to reach Rome. The journey takes about 11 hours 50 minutes and with fares starting at just ARS 23,992, it presents an excellent value for a comfortable ride.
Where are the popular stops in Messina and Rome?
Stops in Messina
- A
Piazza della Repubblica
Via Guido delle Colonne, 49, 98122 Messina ME, Italy - BPiazza Stazione, 98122 Messina ME, Italy
- C
Via Giuseppe Garibaldi 263
Via Giuseppe Garibaldi 263, 98122 Messina ME, Italy - D
Porto
Capitaneria di Porto, Via Vittorio Emanuele II, 111, 98100 Messina ME, Italy
Stops in Rome
- BLargo Guido Mazzoni, 3, 00162 Roma, Italy
- D
Castro Pretorio
Viale Castro Pretorio 76, 00185 Roma, Italy - E
Roma
- F
Anagnina
Via Vincenzo Giudice, 00173 Roma RM, Italy
Compare bus companies
Frequently asked questions about traveling from Messina to Rome by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Messina to Rome?
The cheapest bus tickets from Messina to Rome start from ARS 23,992. The average price for this route is around ARS 74,291. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Messina to Rome?
The average bus trip duration from Messina to Rome is 11h 50m, covering a distance of 302 miles (487 km). The quickest bus can get you there in 9h and is operated by Autoservizi Salemi.
Which bus companies service the Messina to Rome route?
Several major bus companies operate on this route with 9 buses available per day, including services from FlixBus, Itabus, Autoservizi Salemi.
What is the earliest and latest departure time for the bus from Messina to Rome?
The earliest bus departs from Messina to Rome at 12:50am. And the latest bus departs at 11:50pm.
What are the CO₂ emissions for the bus trip from Messina to Rome?
A bus trip from Messina to Rome generates an estimated 12.17105 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Messina to Rome?
According to Busbud customers, the highest-rated bus company on this route is Autoservizi Salemi, with an average rating of 4.3 out of 5 stars based on 489 reviews.
Which bus company has the best Wi-Fi from Messina to Rome?
Based on reviews on Busbud, the bus company Autoservizi Salemi has the best Wi-Fi rating with a score of 4.0.
Which bus company has the most timely service from Messina to Rome?
According to Busbud traveler reviews, the most timely bus company on this route is Autoservizi Salemi, with a punctuality rating of 4.2 out of 5 stars.
Which bus company has the cleanest buses from Messina to Rome?
According to Busbud traveler reviews, the bus company with the cleanest buses on this route is Autoservizi Salemi, with a cleanliness rating of 4.7 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Messina to Rome was searched and found on Apr 20, 2026 with a price of ARS 30,460To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Messina to Rome, as early as possible.
You can expect to pay from ARS 30,460 to ARS 160,788 for a bus ticket from Messina to Rome based on the last 2 days. You can expect to find the cheapest price for the trip at ARS 30,460 which is on 2026-04-20.
Usually FlixBus, Autoservizi Salemi will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Messina to Rome?
The Bus is the cheapest travel choice for this destination
