What is the distance between Mexicali and Guaymas?

The distance separating Mexicali and Guaymas is 424 miles (683 km).

What are the departure and arrival stations when taking the bus from Mexicali to Guaymas?

If you're headed to Guaymas from Mexicali, chances are that your bus will leave from Terminal de Autobuses de Mexicali and arrive at Terminal TAP de Guaymas. These are the main departure and arrival locations on this route, but you can find others that could fit better into your travel plans.

Bus Mexicali to Guaymas from $65 | Refundable Tickets

Previously seen trips

Next departures for Mexicali to Guaymas on November 21
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	7:40pm	Terminal de Autobuses de Mexicali	12h 10m	8:50am	GUAYMAS, SONORA	No tags
Bus	8:20pm	Terminal de Autobuses de Mexicali	13h 30m	10:50am	GUAYMAS, SONORA	No tags
Bus	11:05pm	Terminal de Autobuses de Mexicali	13h 5m	1:10pm	GUAYMAS, SONORA	No tags
Bus	11:30pm	Terminal de Autobuses de Mexicali	12h 5m	12:35pm	GUAYMAS, SONORA	No tags
Bus	11:30pm	Terminal de Autobuses de Mexicali	10h 48m	11:18am	GUAYMAS, SONORA	No tags

Compare 2 ways to go from Mexicali to Guaymas

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach Guaymas. The journey takes about 11 hours 10 minutes and with fares starting at just $73, it presents an excellent value for a comfortable ride.

9bus per day

11h 10mAverage Duration

421 milesDistance

17kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$73 - $94	Average Duration11h 10m	CO₂ emissions 17kg CO₂e
Carpool	Average Price$35 - $35	Average Duration14h 10m	CO₂ emissions 29kg CO₂e

Where are the popular stops in Mexicali and Guaymas?

Stops in Mexicali

A
Terminal de Autobuses de Mexicali
Calzada Independencia No. 1244 (entre Blvd. Anahuac y Lopez Mateos, Col. Centro Civico), 21000 Mexicali
Visit page
B
Nuevo Mexicali
Blvd. Lázaro Cárdenas 2666 -1 , Fraccionamiento, Col. Nuevo Mexicali
C
Restaurant El Mexicano
México 2, Puebla, 21620 Puebla, B.C., Mexico
Visit page
D
Apozol Central 27
Apozol Central 27, Zacatecas, Mexicali, B.C., Mexico
E
Bvld Lázaro Cárdenas
Blvrd Lázaro Cárdenas #3295, Mexicali, B.C., Mexico

Stops in Guaymas

A
Terminal TAP de Guaymas
Calzada Agustín García López #915, Colonia Delicias, 85440 Guaymas

Compare bus companies

Tufesa

3.5/5695 reviews

Staff4.2

Timeliness2.7

Cleanliness4

Wifi3

Since 1994, Tufesa has been offering comfortable, safe, and affordable bus travel in the United States (California, Nevada, Utah, Arizona and Texas) and Mexico (Baja California Sur, Sonora, Sinaloa and Guadalajara). Tufesa buses are equipped with comfortable reclining seats, power outlets, bathrooms, and WiFi (only in Mexico). Tickets are non-refundable, but you can exchange them up to 1 hour before travel time for a small fee. The company accepts e-tickets, so you don't have to worry about printing your boarding pass. With over 7 daily trips, you'll surely find a convenient trip that fits your needs and your schedule.

Aguacaliente

Elite

2.5/5167 reviews

Staff3.3

Timeliness1.2

Cleanliness2.6

Wifi1.2

Aguacaliente

3.5/532 reviews

Staff4

Timeliness2.2

Cleanliness4.1

Wifi2

ELITE SELECT

3/515 reviews

Staff4.6

Timeliness2.3

Cleanliness5

Wifi3.4

MX bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about traveling from Mexicali to Guaymas by bus

What is the distance between Mexicali and Guaymas?
What are the departure and arrival stations when taking the bus from Mexicali to Guaymas?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/18

$65

11/19

$65

Today

$65

11/21

$76

11/22

No data

11/23

No data

11/24

No data

11/25

$76

The cheapest trip from Mexicali to Guaymas was searched and found on Nov 19, 2025 with a price of $65

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mexicali to Guaymas, as early as possible.

You can expect to pay from $65 to $84 for a bus ticket from Mexicali to Guaymas based on the last 2 days. You can expect to find the cheapest price for the trip at $76 which is on 2025-11-21.