Bus Tickets from San Ysidro, CA to Los Angeles, US

Find affordable bus tickets from San Ysidro, CA to Los Angeles, US with flexible options. Book your trip now

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TodayJul 25
from $39
TomorrowJul 26
from $36
SunJul 27
from $34
MonJul 28
from $32
TueJul 29
from $30
WedJul 30
from $30
ThuJul 31
from $30
FriAug 1
from $32

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: July 26 at
    Departure city: San Ysidro
    Departure location: San Ysidro Bus terminal
    Arrival time: July 26 at
    Destination city: Los Angeles
    Destination location: Los Angeles Union Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: July 26 at
    Departure city: San Ysidro
    Departure location: San Ysidro Greyhound Bus Station
    Arrival time: July 26 at
    Destination city: Los Angeles
    Destination location: Los Angeles Bus Station
    Operated by: Los LimousinesLos Limousines
    Vehicle: BusDuration:
  • Departure time: July 26 at
    Departure city: San Ysidro
    Departure location: Mc. Donald´s (San Ysidro Border Crossing)
    Arrival time: July 26 at
    Destination city: Los Angeles
    Destination location: 613 Maple Ave
    Operated by: TufesaTufesa
    Vehicle: BusDuration:
  • Departure time: July 26 at
    Departure city: San Ysidro
    Departure location: San Ysidro Bus terminal
    Arrival time: July 26 at
    Destination city: Los Angeles
    Destination location: Los Angeles Union Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: July 26 at
    Departure city: San Ysidro
    Departure location: San Ysidro Bus terminal
    Arrival time: July 26 at
    Destination city: Los Angeles
    Destination location: Los Angeles Union Station
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:

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Bus San Ysidro, CA to Los Angeles, US: Trip Overview

Average ticket price$43
Average bus trip duration4h 10m
Number of daily buses49
Earliest bus departure1:15am
Distance125 miles (201 km)
Latest bus departure10:00pm

San Ysidro to Los Angeles Bus

Busbud helps you find a bus from San Ysidro to Los Angeles. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from San Ysidro to Los Angeles.

Discover how much the bus trip from San Ysidro to Los Angeles will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip San Ysidro, CA - Los Angeles, US

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
07/23
$37
07/24
$28
Today
$34
07/26
$28
07/27
$27
07/28
$24
07/29
$23
07/30
$22
busbud logoThe cheapest trip from San Ysidro, CA to Los Angeles, US was searched and found on Jul 30, 2025 with a price of $22

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Ysidro, CA to Los Angeles, US, as early as possible.

You can expect to pay from $22 to $59 for a bus ticket from San Ysidro, CA to Los Angeles, US based on the last 2 days. You can expect to find the cheapest price for the trip at $22 which is on 2025-07-30.

Usually Tufesa will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between San Ysidro and Los Angeles!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from San Ysidro to Los Angeles.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from San Ysidro to Los Angeles will emit less CO2 than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from San Ysidro to Los Angeles while indulging in miles on end of beautiful scenic views.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Will you be returning to San Ysidro, CA by bus?

Bus from San Ysidro, CA to Los Angeles, US

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