Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Greyhound Station | Spartanburg | Cheapest | ||||
| Bus | Greyhound Station | Spartanburg | Fastest |
Last refresh of the prices: Last Wednesday at 4:50 AM CST.
Get from Mobile to Spartanburg
The journey takes about 10 hours 40 minutes and with fares starting at just $88, it presents an excellent value for a comfortable ride.
Where are the popular stops in Mobile and Spartanburg?
Stops in Spartanburg
- A9133 Fairforest Rd. Spartanburg, SC , C.P. 29301
- B
Spartanburg Bus Stop
1402 E Main St, Spartanburg, SC 29307, USA - C
Sparta Passenger Center
100 Liberty St, Spartanburg, SC 29306, USA
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Mobile to Spartanburg by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Mobile to Spartanburg?
The cheapest bus tickets from Mobile to Spartanburg start from $88. The average price for this route is around $154. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Mobile to Spartanburg?
The average bus trip duration from Mobile to Spartanburg is 10h 40m, covering a distance of 463 miles (746 km). The quickest bus can get you there in 10h 40m and is operated by Greyhound.
Which bus companies service the Mobile to Spartanburg route?
Several major train operators operate on this route with 1 trains available per day.
What is the earliest and latest departure time for the bus from Mobile to Spartanburg?
The earliest bus departs from Mobile to Spartanburg at 12:05am. And the latest bus departs at 3:55pm.
What are the CO₂ emissions for the bus trip from Mobile to Spartanburg?
A bus trip from Mobile to Spartanburg generates an estimated 19 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Mobile to Spartanburg was searched and found on Jan 8, 2026 with a price of $80To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mobile to Spartanburg, as early as possible.
You can expect to pay from $80 to $103 for a bus ticket from Mobile to Spartanburg based on the last 2 days. You can expect to find the cheapest price for the trip at $88 which is on 2026-01-13.
