Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | GW Bridge | 1116 Woodruff Rd | Cheapest | |||||
 | 103 Canal St | 1111 Woodruff Road | Fastest | |||||
| 103 Canal St | 1111 Woodruff Road | No tags | |||||
Greyhound Lines, Inc. + FlixBus | New York Port Authority | 1116 Woodruff Rd | No tags | |||||
 | New York Port Authority | 1116 Woodruff Rd | No tags |
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Compare 2 ways to go from New York City to Greenville.
Busbud recommends taking the train from New York City to GreenvilleAmong the sustainable travel choices, the train stands out as the good way to reach Greenville. The journey takes about 15 hours 24 minutes and with fares starting at just $108, it presents an excellent value for a comfortable ride.
Bus New York City to Greenville, SC: Trip Overview
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New York City to Greenville Bus
Busbud helps you find a bus from New York City to Greenville. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
Bus service from New York City to Greenville will be provided by the most trusted bus companies.
From cheap bus tickets to more luxurious buses traveling from New York City to Greenville, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in New York City and Greenville?
Frequently asked questions for your trip New York City - Greenville, SC
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from New York City to Greenville, SC was searched and found on Aug 22, 2025 with a price of $91To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from New York City to Greenville, SC, as early as possible.
You can expect to pay from $91 to $154 for a bus ticket from New York City to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at $91 which is on 2025-08-25.
Usually Wanda Coach will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between New York City and Greenville!
Much more than a mere vehicle taking you from New York City to Greenville, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from New York City to Greenville that are otherwise impossible to come by with a plane.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from New York City to Greenville.
Did you know?
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
What's the cheapest way to go from New York City to Greenville, SC?
The bus is the cheapest travel choice for this destinationTop traveled bus routes
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