Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Opelika (4th Street Station) | Birmingham Greyhound Bus Station | CheapestFastest |
Last refresh of the prices: Yesterday at 5:59 PM CST.
Get from Opelika to Birmingham
The journey takes about 2 hours 35 minutes and with fares starting at just $28, it presents an excellent value for a comfortable ride.
Where are the popular stops in Opelika and Birmingham?
Stops in Opelika
- A
McDonald's - Opelika
1104 Columbus Pkwy, Opelika, AL 36801, USA
Stops in Birmingham
- A
Birmingham Greyhound Bus Station
1801 Morris Ave, 35203 Birmingham, AL - B2427 Acton Rd, Vestavia Hills, AL 35243, USA
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Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Opelika to Birmingham, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Opelika to Birmingham?
The cheapest bus tickets from Opelika to Birmingham start from $28. The average price for this route is around $29. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Opelika to Birmingham?
The average bus trip duration from Opelika to Birmingham is 2h 35m, covering a distance of 103 miles (166 km). The quickest bus can get you there in 2h 35m and is operated by Greyhound.
Which bus companies service the Opelika to Birmingham route?
Several major train operators operate on this route with 1 trains available per day.
What is the earliest and latest departure time for the bus from Opelika to Birmingham?
The earliest bus departs from Opelika to Birmingham at 1:25pm. And the latest bus departs at 1:25pm.
What are the CO₂ emissions for the bus trip from Opelika to Birmingham?
A bus trip from Opelika to Birmingham generates an estimated 4 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Opelika to Birmingham, US was searched and found on Nov 26, 2025 with a price of $29To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Opelika to Birmingham, US, as early as possible.
