Bus Tickets from Tupelo, MS to Columbia, MO

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Bus Tupelo to Columbia: Trip Overview

Average ticket price$91
Average bus trip duration18h 15m
Number of daily buses4
Earliest bus departure5:35am
Distance387 miles (624 km)
Latest bus departure9:35pm

Tupelo to Columbia Bus

Busbud helps you find a bus from Tupelo to Columbia. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Tupelo to Columbia from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses traveling from Tupelo to Columbia, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip Tupelo - Columbia

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05/08
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05/09
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Today
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05/11
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05/12
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05/13
$72
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05/15
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busbud logoThe cheapest trip from Tupelo to Columbia was searched and found on May 13, 2025 with a price of $72

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Tupelo to Columbia, as early as possible.

You can expect to pay from $72 to $72 for a bus ticket from Tupelo to Columbia based on the last 2 days. You can expect to find the cheapest price for the trip at $72 which is on 2025-05-13.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Tupelo and Columbia!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Tupelo to Columbia, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Tupelo to Columbia that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from Tupelo to Columbia, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Will you be returning to Tupelo by bus?

Bus from Tupelo to Columbia

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