Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Based on 944 reviews, the company was rated 3.8 stars on Busbud. Travelers were especially satisfied with the ticket access and the temperature but often complained with the timeliness. Itabus ticket prices on this trip start at $42
Piazza Antonio Gramsci, 53100 Siena SI, ItalyPiazza Gramsci
B - Via Sallustio Bandini, 21
Via Sallustio Bandini, 21, 53100 Siena SI, Italy
C - Via Giuseppe Mazzini, 58
Via Giuseppe Mazzini, 58, 53100 Siena SI, Italy
D - Via Riccardo Lombardi, 42
Via Riccardo Lombardi, 42, 53100 Siena SI, Italy
E - Torre Fiorentina
Torre Fiorentina, 53100 Siena SI, Italy
F - Siena Zona Industriale
Siena FS, 53100 Siena SI, Italy
Frequently asked questions about traveling from Zürich to Siena by bus
How far is Zürich from Siena?
The distance between the two cities is 311 miles (501 km).
What are the departure and arrival stations when taking the bus from Zürich to Siena?
Most of the buses traveling from Zürich to Siena leave from Zürich Airport and arrive at Piazza Gramsci. These are the primary departure and arrival locations on this route, there are other pick-up and drop-off locations that could make it easier for you to reach your destination.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/18
$50
11/19
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Today
$50
11/21
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11/22
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11/23
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11/24
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11/25
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The cheapest trip from Zürich to Siena was searched and found on Nov 20, 2025 with a price of $50
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Zürich to Siena, as early as possible.
The cheapest trip from Zürich to Siena was searched and found on Nov 20, 2025 with a price of $50
