How much is the train ticket from San Diego to Indianapolis?

The cheapest train tickets from San Diego to Indianapolis start from $396. The average price for this train route is around $1,479. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the train journey from San Diego to Indianapolis?

The average train ride duration from San Diego to Indianapolis is 2d 6h, covering a distance of 1782 miles (2874 km). The quickest train can get you there in 2d 6h and is operated by Amtrak .

Which train operators service the San Diego to Indianapolis route?

Several major train operators operate on this route with 2 trains available per day.

What is the earliest and latest departure time for the train from San Diego to Indianapolis?

The earliest train departs from San Diego to Indianapolis at 2:01pm. And the latest train departs at 4:10pm.

Train San Diego to Indianapolis from $243 | Refundable Tickets

Next departures

Next departures for San Diego to Indianapolis on December 22
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
		2:01pm	Santa Fe Depot	2d 9h	2:50am	Greyhound Amtrak Station	Cheapest
		2:10pm	Old Town San Diego	2d 9h	2:50am	Greyhound Amtrak Station	Fastest

Next departures for San Diego to Indianapolis on December 23
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
2:01pm	Santa Fe Depot	2d 6h	11:49pm	Greyhound Amtrak Station	Cheapest
2:10pm	Old Town San Diego	2d 6h	11:49pm	Greyhound Amtrak Station	Fastest
2:01pm	Santa Fe Depot	2d 6h	11:49pm	Greyhound Amtrak Station	No tags
2:01pm	Santa Fe Depot	2d 6h	11:49pm	Greyhound Amtrak Station	No tags
2:01pm	Santa Fe Depot	2d 9h	2:50am	Greyhound Amtrak Station	No tags

Next departures for San Diego to Indianapolis on December 24
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
4:01pm	Santa Fe Depot	3d 4h	11:49pm	Greyhound Amtrak Station	Cheapest
2:10pm	Old Town San Diego	2d 9h	2:50am	Greyhound Amtrak Station	Fastest
2:01pm	Santa Fe Depot	2d 9h	2:50am	Greyhound Amtrak Station	No tags
4:01pm	Santa Fe Depot	3d 4h	11:49pm	Greyhound Amtrak Station	No tags
4:01pm	Santa Fe Depot	3d 4h	11:49pm	Greyhound Amtrak Station	No tags

Last refresh of the prices: Yesterday at 7:00 PM PST.

Compare 2 ways to go from San Diego to Indianapolis

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach Indianapolis. The journey takes about 2 days, 6 hours 55 minutes and with fares starting at just $288, it presents an excellent value for a comfortable ride.

20bus per day

2d 6hAverage Duration

1780 milesDistance

72kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$288 - $726	Average Duration2d 6h	CO₂ emissions 72kg CO₂e
Train	Average Price$396 - $1,532	Average Duration2d 6h	CO₂ emissions 262kg CO₂e

Train Companies

Amtrak

4/55,666 reviews

Staff4.7

Timeliness3.8

Cleanliness4.6

Wifi3.6

Based on 5666 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $308

Train and bus companies in US:Amtrak, Trenitalia, Renfe, VIA Rail Canada, Amtrak Acela, NS Nederlandse Spoorwegen, Iryo

Frequently asked questions about traveling from San Diego, CA, US to Indianapolis by train

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the train ticket from San Diego to Indianapolis?
The cheapest train tickets from San Diego to Indianapolis start from $396. The average price for this train route is around $1,479. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the train journey from San Diego to Indianapolis?
The average train ride duration from San Diego to Indianapolis is 2d 6h, covering a distance of 1782 miles (2874 km). The quickest train can get you there in 2d 6h and is operated by Amtrak.
Which train operators service the San Diego to Indianapolis route?
Several major train operators operate on this route with 2 trains available per day.
What is the earliest and latest departure time for the train from San Diego to Indianapolis?
The earliest train departs from San Diego to Indianapolis at 2:01pm. And the latest train departs at 4:10pm.

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

12/20

$2,676

12/21

$1,790

Today

$1,453

12/23

$433

12/24

$593

12/25

No data

12/26

No data

12/27

No data

The cheapest trip from San Diego, CA, US to Indianapolis was searched and found on Dec 23, 2025 with a price of $433

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from San Diego, CA, US to Indianapolis, as early as possible.

You can expect to pay from $433 to $2,676 for a train ticket from San Diego, CA, US to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at $433 which is on 2025-12-23.