Compare 2 ways to go from San Diego to Indianapolis.
Busbud recommends taking the train from San Diego to IndianapolisAmong the sustainable travel choices, the train stands out as the good way to reach Indianapolis. The journey takes about 2 days, 9 hours 45 minutes and with fares starting at just $208, it presents an excellent value for a comfortable ride.
Bus San Diego to Indianapolis: Trip Overview
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San Diego to Indianapolis Bus
Busbud helps you find a bus from San Diego to Indianapolis. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make sure you can find a bus service from San Diego to Indianapolis from the most reliable bus companies operating this trip.
From cheap bus tickets to more luxurious buses traveling from San Diego to Indianapolis, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in San Diego and Indianapolis?
Frequently asked questions for your trip San Diego, CA, US - Indianapolis
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from San Diego to Indianapolis was searched and found on Jun 22, 2025 with a price of $123To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Diego to Indianapolis, as early as possible.
You can expect to pay from $123 to $184 for a bus ticket from San Diego to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at $172 which is on 2025-06-26.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between San Diego and Indianapolis!
Start sightseeing the minute your bus leaves the station. If you're on the night bus from San Diego to Indianapolis, get comfy and count the stars.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from San Diego to Indianapolis that are otherwise impossible to come by with a plane.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from San Diego to Indianapolis.
Did you know?
Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
Top traveled bus routes
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Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.
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