Bus Tickets from Avignon to Brussels

Find affordable bus tickets from Avignon to Brussels with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.
TodayMay 11
from US$141
TomorrowMay 12
from US$98
TueMay 13
from US$87
WedMay 14
ThuMay 15
from US$66
FriMay 16
from US$87
SatMay 17
SunMay 18

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: May 12 at
    Departure city: Avignon
    Departure location: Avignon (Le Pontet)
    Arrival time: May 12 at
    Destination city: Brussels
    Destination location: Brussels-South (Gare du Midi)
    Operated by: BlaBlaCar BusBlaBlaCar Bus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: May 12 at
    Departure city: Avignon
    Departure location: Avignon (Le Pontet)
    Arrival time: May 13 at
    Destination city: Brussels
    Destination location: Brussels-South (Gare du Midi)
    Operated by: BlaBlaCar BusBlaBlaCar Bus
    Vehicle: BusDuration:
  • Departure time: May 12 at
    Departure city: Avignon
    Departure location: Avignon (Le Pontet)
    Arrival time: May 13 at
    Destination city: Brussels
    Destination location: Brussels-South (Gare du Midi)
    Operated by: BlaBlaCar BusBlaBlaCar Bus
    Vehicle: BusDuration:

Last refresh of the prices: Last Thursday at 11:59 AM CEST.

Prices and availability are subject to change.

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 3 ways to go from Avignon to Brussels

Bus
Average PriceUS$50 - US$261Average Duration14h 40m
19kg CO₂e5 out of 5 stars
Cheapest
Train
Average PriceUS$181 - US$391Average Duration5h 34m
18kg CO₂e5 out of 5 stars
FastestMost eco-friendly
Carpool
Average PriceUS$146 - US$146Average Duration10h 40m
32kg CO₂e4 out of 5 stars
busbud logoBusbud recommends taking the train from Avignon to Brussels

Among the sustainable travel choices, the train stands out as a good way to reach Brussels. The journey takes about 5 hours 34 minutes, and with fares starting at just US$181, it presents an excellent value for a comfortable ride.

9train per day
5h 34mAverage Duration
US$181Cheapest ticket
18kgCO₂ emissions

Bus Avignon to Brussels: Trip Overview

Average Ticket PriceUS$80
Average Bus Trip Duration14h 40m
Number of daily buses3
Earliest bus departure12:10am
Distance768 km
Latest bus departure10:20pm

Avignon to Brussels Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Avignon to Brussels.

Bus service from Avignon to Brussels will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses travelling from Avignon to Brussels, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Avignon - Brussels

  1. How long is the trip from Avignon to Brussels by bus?

    The typical travel time from Avignon to Brussels by bus is around 14h 40m. For the shortest travel time, select the fastest bus available, which will take you to Brussels in about 12h 20m.

  2. What is the travel distance from Avignon to Brussels?

    The distance between Avignon and Brussels is around 770 km (477 miles).

  3. What are the departure and arrival locations for buses traveling from Avignon to Brussels?

    Buses traveling this route start their trip at Gare Routière Avignon, in Avignon, and end it at Brussels South (Gare du Midi), in Brussels.

  4. What is the cheapest way to go from Avignon to Brussels?

    The least expensive way to go from Avignon to Brussels would be going by bus. With a starting ticket price of US$50, this bus becomes your top pick for this journey.

  5. How much does the bus ticket cost from Avignon to Brussels?

    The bus fare from Avignon to Brussels is approximately US$80.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05-09
US$102
05-10
US$197
Today
US$132
05-12
US$92
05-13
US$81
05-14
US$56
05-15
US$62
05-16
US$81
busbud logoThe cheapest trip from Avignon to Brussels was searched and found on May 14, 2025 with a price of US$56

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Avignon to Brussels, as early as possible.

You can expect to pay from US$56 to US$246 for a bus ticket from Avignon to Brussels based on the last 2 days. You can expect to find the cheapest price for the trip at US$56 which is on 2025-05-14.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Avignon to Brussels but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from Avignon to Brussels, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Avignon to Brussels that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Avignon to Brussels.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

What's the cheapest way to go from Avignon to Brussels?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Avignon by bus?

Bus from Avignon to Brussels

You can also go to Brussels by train

Train from Avignon to Brussels

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

‌

Popular Buses Connecting Avignon

Buses Leaving from Avignon

Buses Going to Avignon

Popular Buses Connecting Brussels

Buses Leaving from Brussels

Buses Going to Brussels