Next departures for Avignon to Brussels on November 21
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Avignon (Le Pontet)
Brussels Airport
Cheapest
Bus
Avignon (Le Pontet)
Brussels-South (Gare du Midi)
Fastest
Bus
Avignon (Le Pontet)
Brussels-South (Gare du Midi)
No tags
Bus
Avignon (Le Pontet)
Brussels North Train Station
No tags
Bus
Avignon (Le Pontet)
Brussels South (Gare du Midi)
No tags
Next departures for Avignon to Brussels on November 22
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Avignon (Le Pontet)
Brussels-South (Gare du Midi)
CheapestFastest
Bus
Avignon (Le Pontet)
Brussels-South (Gare du Midi)
No tags
Next departures for Avignon to Brussels on November 23
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Avignon (Le Pontet)
Brussels-South (Gare du Midi)
CheapestFastest
Bus
Avignon (Le Pontet)
Brussels-South (Gare du Midi)
No tags
Next departures for Avignon to Brussels on November 24
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Avignon (Le Pontet)
Brussels-South (Gare du Midi)
CheapestFastest
Bus
Avignon (Le Pontet)
Brussels-South (Gare du Midi)
No tags
Last refresh of the prices: Yesterday at 9:04 PM CET.
Compare 3 ways to go from Avignon to Brussels
We recommend carpooling
Among the sustainable travel choices, the carpool stands out as the good way to reach Brussels. The journey takes about 10 hours 30 minutes and with fares starting at just $98, it presents an excellent value for a comfortable ride.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Based on 11143 reviews, the company was rated 3.7 stars on Busbud. Travelers were especially satisfied with the ticket access and the staff but often complained with the wifi. BlaBlaCar Bus ticket prices on this trip start at $53
Frequently asked questions about traveling from Avignon to Brussels by bus
What is the travel distance from Avignon to Brussels?
About 477 miles (770 km) separate Avignon and Brussels.
What are the departure and arrival stations when taking the bus from Avignon to Brussels?
The majority of buses traveling from Avignon to Brussels start their journey at Gare Routière Avignon and wind up at Brussels South (Gare du Midi). These are the main pick-up and drop-off locations on this route, but you could find others that could be a better fit for your travel plans.
What are the best sights and things to do in Brussels?
Once in Brussels, you can start exploring the city and discover its surroundings. The top sights and things to do are The Brussels Flower Carpet, a major event on the Grand Place, Fête de la BD - Comic Festival in Brussels! Belgian Beer Weekend in Brussels! The Ommegang, Brussels' oldest historical pageant and Couleur Café Music Festival.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/19
$92
11/20
$48
Today
$47
11/22
$95
11/23
$89
11/24
$82
11/25
$47
11/26
$57
The cheapest trip from Avignon to Brussels was searched and found on Nov 21, 2025 with a price of $47
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Avignon to Brussels, as early as possible.
You can expect to pay from $47 to $148 for a bus ticket from Avignon to Brussels based on the last 2 days. You can expect to find the cheapest price for the trip at $47 which is on 2025-11-25.
What's the cheapest way to go from Avignon to Brussels?
The bus is the cheapest travel choice for this destination
The cheapest trip from Avignon to Brussels was searched and found on Nov 21, 2025 with a price of $47
The bus is the cheapest travel choice for this destination
