Bus Tickets from Buffalo, NY to Spartanburg, SC

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TodayMay 11
from US$125
TomorrowMay 12
TueMay 13
WedMay 14
ThuMay 15
FriMay 16
SatMay 17
SunMay 18

Cheap buses leaving today

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: May 11 at
    Departure city: Buffalo
    Departure location: Niagara Frontier Transportation Authority
    Arrival time: May 13 at
    Destination city: Spartanburg
    Destination location: Spartanburg
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: May 11 at
    Departure city: Buffalo
    Departure location: Buffalo (BUF) Airport
    Arrival time: May 12 at
    Destination city: Spartanburg
    Destination location: Spartanburg
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: May 11 at
    Departure city: Buffalo
    Departure location: Niagara Frontier Transportation Authority
    Arrival time: May 12 at
    Destination city: Spartanburg
    Destination location: Spartanburg
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: May 11 at
    Departure city: Buffalo
    Departure location: Niagara Frontier Transportation Authority
    Arrival time: May 12 at
    Destination city: Spartanburg
    Destination location: Spartanburg
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: May 11 at
    Departure city: Buffalo
    Departure location: Buffalo (BUF) Airport
    Arrival time: May 12 at
    Destination city: Spartanburg
    Destination location: Spartanburg
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

Last refresh of the prices: 2025-05-04 EDT.

Prices and availability are subject to change.

Accepted payments

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Compare 2 ways to go from Buffalo to Spartanburg

Average PriceUS$121 - US$283Average Duration1d 4h
23kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Average PriceUS$318 - US$404Average Duration23h 36m
84kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the train from Buffalo to Spartanburg

Among the sustainable travel choices, the train stands out as a good way to reach Spartanburg. The journey takes about 23 hours 36 minutes, and with fares starting at just US$318, it presents an excellent value for a comfortable ride.

2train per day
23h 36mAverage Duration
US$318Cheapest ticket
84kgCO₂ emissions

Bus Buffalo to Spartanburg: Trip Overview

Average Ticket PriceUS$154
Average Bus Trip Duration1d 4h
Number of daily buses6
Earliest bus departure7:50am
Distance926 km
Latest bus departure11:59pm

Buffalo to Spartanburg Bus

Busbud helps you find a bus from Buffalo to Spartanburg. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from Buffalo to Spartanburg will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to Spartanburg from Buffalo, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Buffalo - Spartanburg

  1. How long does it take to get to Spartanburg from Buffalo by bus?

    The typical travel time from Buffalo to Spartanburg by bus is around 1d 4h. For the shortest travel time, select the fastest bus available, which will take you to Spartanburg in about 23h 20m.

  2. What is the distance between Buffalo and Spartanburg?

    The distance covered from Buffalo to Spartanburg is 923 km (572 miles).

  3. What are the departure and arrival locations for buses traveling from Buffalo to Spartanburg?

    Buses traveling this route start their trip at Buffalo Airport, in Buffalo, and end it at Super Acapulco, in Spartanburg.

  4. What is the cheapest way to go from Buffalo to Spartanburg?

    The least expensive option to go from Buffalo to Spartanburg would be going by bus. Starting at US$121, this bus is the most cost-effective option for your journey.

  5. How much is the bus from Buffalo to Spartanburg?

    The bus fare from Buffalo to Spartanburg is approximately US$154.

  6. Is it possible to travel by overnight bus from Buffalo to Spartanburg?

    Yes! Catch buses leaving from Buffalo until 11:59pm and reaching Spartanburg on the following day.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Buffalo and Spartanburg!

Much more than a mere vehicle taking you from Buffalo to Spartanburg, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Buffalo to Spartanburg.

Tune out to the fine sounds of your best music playlist on your bus trip from Buffalo to Spartanburg while indulging in miles on end of beautiful scenic views.

Did you know?

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

What's the cheapest way to go from Buffalo to Spartanburg?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Buffalo by bus?

Bus from Buffalo to Spartanburg

You can also go to Spartanburg by train

Train from Buffalo to Spartanburg

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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