Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Buffalo, NY (181 Ellicott St, Buffalo, NY 14203, United States) | Super Acapulco | No tags | ||||
Greyhound + FlixBus | Bus | Buffalo, NY (181 Ellicott St, Buffalo, NY 14203, United States) | Super Acapulco | No tags | ||||
Greyhound + FlixBus | Bus | Buffalo (BUF) Airport | Super Acapulco | No tags | ||||
FlixBus + Greyhound | Bus | Buffalo (BUF) Airport | Super Acapulco | No tags | ||||
FlixBus + Greyhound | Bus | Buffalo, NY (181 Ellicott St, Buffalo, NY 14203, United States) | Super Acapulco | No tags |
Compare 2 ways to go from Buffalo to Spartanburg
Among the sustainable travel choices, the train stands out as the good way to reach Spartanburg. The journey takes about 23 hours 36 minutes and with fares starting at just $236, it presents an excellent value for a comfortable ride.
Where are the popular stops in Buffalo and Spartanburg?
Stops in Buffalo
- B185 Ellicott St, Buffalo, NY 14203, USA
- C75 Exchange St, Buffalo, NY 14203, USA
Stops in Spartanburg
- A9133 Fairforest Rd. Spartanburg, SC , C.P. 29301
- B
Spartanburg Bus Stop
1402 E Main St, Spartanburg, SC 29307, USA - C
Sparta Passenger Center
100 Liberty St, Spartanburg, SC 29306, USA
Compare bus companies
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Frequently asked questions about traveling from Buffalo, NY to Spartanburg by bus
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Buffalo, NY to Spartanburg was searched and found on Nov 28, 2025 with a price of $168To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Buffalo, NY to Spartanburg, as early as possible.
You can expect to pay from $168 to $216 for a bus ticket from Buffalo, NY to Spartanburg based on the last 2 days. You can expect to find the cheapest price for the trip at $168 which is on 2025-11-28.
What's the cheapest way to go from Buffalo, NY to Spartanburg?
The bus is the cheapest travel choice for this destination
