Bus Tickets from Charlotte, NC to Panama City, US

Next departures

Next departures for Charlotte to Panama City on October 13
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound Lines, Inc.
Charlotte (Freedom Dr)
Panama City Beach StationCheapest
Greyhound Lines, Inc.
Charlotte Bus Station
Panama City Beach StationFastest
FlixBus + Greyhound Lines, Inc.
Charlotte Bus Station
Panama City Beach StationNo tags
Greyhound Lines, Inc.
Charlotte Bus Station
Panama City Beach StationNo tags
Greyhound Lines, Inc.
Charlotte Bus Station
Panama City Beach StationNo tags

Last refresh of the prices: Today at 5:45 AM EDT.

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Bus Charlotte, NC to Panama City, US: Trip Overview

Average Ticket PriceUS$113
Average Bus Trip Duration19h 25m
Number of daily buses5
Earliest bus departure5:05am
Distance725 km
Latest bus departure10:30pm

Charlotte to Panama City Bus

With Busbud, comparing and booking tickets for a bus from Charlotte to Panama City is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Charlotte to Panama City.

Discover how much the bus trip from Charlotte to Panama City will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Charlotte, NC - Panama City, US

  1. What is the distance between Charlotte and Panama City?

    The distance between Charlotte and Panama City is around 723 km (449 miles).

  2. What are the departure and arrival locations for buses traveling from Charlotte to Panama City?

    Buses traveling this route start their trip at Tornado & El Expreso Bus Company, in Charlotte, and end it at Panama City Greyhound Bus Station, in Panama City.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10-10
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10-11
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Today
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10-13
US$118
10-14
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10-15
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10-16
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10-17
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busbud logoThe cheapest trip from Charlotte, NC to Panama City, US was searched and found on Oct 13, 2025 with a price of US$118

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Charlotte, NC to Panama City, US, as early as possible.

You can expect to pay from US$118 to US$118 for a bus ticket from Charlotte, NC to Panama City, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$118 which is on 2025-10-13.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Charlotte to Panama City.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Charlotte to Panama City.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Charlotte to Panama City will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from Charlotte to Panama City, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Will you be returning to Charlotte, NC by bus?

Bus from Panama City, US to Charlotte, NC

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