Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Charlotte Bus Station | Panama City Beach Station | CheapestFastest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Charlotte Bus Station | Panama City Beach Station | No tags | ||||
| Bus | Charlotte Bus Station | Panama City Beach Station | No tags | ||||
| Bus | Charlotte Bus Station | Panama City Beach Station | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Charlotte (Uptown) | Panama City Beach Station | No tags |
Last refresh of the prices: Last Thursday at 7:01 AM EST.
Get from Charlotte to Panama City
The journey takes about 19 hours 15 minutes, and with fares starting at just $160, it presents an excellent value for a comfortable ride.
Where are the popular stops in Charlotte and Panama City?
Stops in Charlotte
- A
Tornado & El Expreso Bus Company
4705 N. Tryon S, Charlotte, NC, USA - C
Charlotte Greyhound Bus Station
601 W Trade St , Charlotte, NC 28202 - D
Agencia El Salvador Bus Stop
4335 N Tryon St, Charlotte, NC 28213 - E
4127 Glenwood Dr
4127 Glenwood Dr, Charlotte, NC 28208 (Exxon Gas Station)
Compare bus companies
Frequently asked questions about travelling from Charlotte, NC to Panama City, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Charlotte to Panama City?
The cheapest bus tickets from Charlotte to Panama City start from $160. The average price for this route is around $214. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Charlotte to Panama City?
The average bus travel time from Charlotte to Panama City is 19h 15m, covering a distance of 724 km. The quickest bus can get you there in 16h 30m and is operated by Greyhound.
Which bus companies service the Charlotte to Panama City route?
What are the earliest and latest departure times for the bus from Charlotte to Panama City?
The earliest bus departs from Charlotte to Panama City at 12:55am. And the latest bus departs at 10:30pm.
What are the CO₂ emissions for the bus trip from Charlotte to Panama City?
A bus trip from Charlotte to Panama City generates an estimated 18 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Charlotte to Panama City?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87500 reviews.
Which bus company has the best Wi-Fi from Charlotte to Panama City?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Charlotte to Panama City?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Charlotte to Panama City?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Charlotte, NC to Panama City, US was searched and found on Jan 20, 2026 with a price of $150To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Charlotte, NC to Panama City, US, as early as possible.
You can expect to pay from $150 to $189 for a bus ticket from Charlotte, NC to Panama City, US based on the last 2 days. You can expect to find the cheapest price for the trip at $150 which is on 2026-01-20.
