Find coaches from Charlotte, NC to Panama City, US

Previously seen journeys

Next departures from Charlotte to Panama City on 24 September
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound
Charlotte Bus Station
Panama City Beach StationNo tags
Greyhound + FlixBus
Charlotte (Uptown)
Panama City Beach StationNo tags
FlixBus + Greyhound
Charlotte (Freedom Dr)
Panama City Beach StationNo tags
Greyhound
Charlotte Bus Station
Panama City Beach StationNo tags
Greyhound
Charlotte Bus Station
Panama City Beach StationNo tags

Accepted payments

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  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus Charlotte, NC to Panama City, US: Trip Overview

Average ticket priceUS$129
Average bus trip duration19h 40m
Number of daily buses5
Earliest bus departure05:05
Distance450 miles
Latest bus departure22:30

Charlotte to Panama City Bus

With Busbud, comparing and booking tickets for a bus from Charlotte to Panama City is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Charlotte to Panama City.

Discover how much the bus trip from Charlotte to Panama City will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Charlotte, NC - Panama City, US

  1. What's the distance between Charlotte and Panama City by coach?

    The distance between Charlotte and Panama City by coach is approximately 449 miles (723 km).

  2. What is the best way to go from Charlotte to Panama City without flying?

    You have the option to select the coach for your journey on this route. The coach ensures a pleasant travel experience, granting you the opportunity to appreciate the scenery as you make your way to your final stop. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
22/09
No data
23/09
No data
Today
No data
25/09
No data
26/09
No data
27/09
No data
28/09
US$77
29/09
No data
busbud logoThe cheapest trip from Charlotte, NC to Panama City, US was searched and found on 28 Sept 2025 with a price of US$77

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Charlotte, NC to Panama City, US as early as possible.

You can expect to pay from US$77 to US$87 for a bus ticket from Charlotte, NC to Panama City, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$77, which is on 2025-09-28.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Charlotte to Panama City.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Charlotte to Panama City.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Charlotte to Panama City will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Make a music playlist for your bus ride from Charlotte to Panama City, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Will you be returning to Charlotte, NC by bus?

Bus from Panama City, US to Charlotte, NC

Why choose Busbud?

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