Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | Downtown Greyhound Station | Harrisburg Bus Station | Cheapest | ||||
 | Bus | Downtown Greyhound Station | Harrisburg Bus Station | Fastest | ||||
| Bus | Downtown Greyhound Station | Harrisburg Bus Station | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Chicago 95Th & Dan Ryan | Harrisburg Bus Station | No tags | ||||
| Bus | 537-517 W. Jackson Blvd | Harrisburg Bus Station | No tags |
Last refresh of the prices: Today at 10:30 AM CST.
Compare 2 ways to go from Chicago to Harrisburg
Among the sustainable travel choices, the bus stands out as a good way to reach Harrisburg. The journey takes about 17 hours, and with fares starting at just $118, it presents an excellent value for a comfortable ride.
Where are the popular stops in Chicago and Harrisburg?
Stops in Chicago
- A630 W Harrison St, Chicago, IL 60607, USA
- C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA - D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA - E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA - F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA
Stops in Harrisburg
- A
Harrisburg Bieber Greyhound Station
411 Market St, Harrisburg, PA 17101
Compare bus companies
Frequently asked questions about travelling from Chicago to Harrisburg by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Chicago to Harrisburg?
The cheapest bus tickets from Chicago to Harrisburg start from $118. The average price for this route is around $188. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Chicago to Harrisburg?
The average bus travel time from Chicago to Harrisburg is 17h, covering a distance of 916 km. The quickest bus can get you there in 15h 15m and is operated by Greyhound.
Which bus companies service the Chicago to Harrisburg route?
What are the earliest and latest departure times for the bus from Chicago to Harrisburg?
The earliest bus departs from Chicago to Harrisburg at 5:25am. And the latest bus departs at 11:40pm.
What are the CO₂ emissions for the bus trip from Chicago to Harrisburg?
A bus trip from Chicago to Harrisburg generates an estimated 23 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Chicago to Harrisburg?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87412 reviews.
Which bus company has the best Wi-Fi from Chicago to Harrisburg?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Chicago to Harrisburg?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Chicago to Harrisburg?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Chicago to Harrisburg was searched and found on Dec 10, 2025 with a price of $160To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Harrisburg, as early as possible.
You can expect to pay from $160 to $282 for a bus ticket from Chicago to Harrisburg based on the last 2 days. You can expect to find the cheapest price for the trip at $160 which is on 2025-12-10.
What's the cheapest way to go from Chicago to Harrisburg?
The bus is the cheapest travel choice for this destination
