Next departures for Chicago to Harrisburg on December 12
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Chicago 95Th & Dan Ryan
Harrisburg Bus Station
Cheapest
Bus
Downtown Greyhound Station
Harrisburg Bus Station
Fastest
Bus
Downtown Greyhound Station
Harrisburg Bus Station
No tags
Bus
Downtown Greyhound Station
Harrisburg Bus Station
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Chicago 95Th & Dan Ryan
Harrisburg Bus Station
No tags
Next departures for Chicago to Harrisburg on December 13
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Downtown Greyhound Station
Harrisburg Bus Station
Cheapest
Bus
Downtown Greyhound Station
Harrisburg Bus Station
Fastest
Bus
Downtown Greyhound Station
Harrisburg Bus Station
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Chicago 95Th & Dan Ryan
Harrisburg Bus Station
No tags
Bus
Chicago 95Th & Dan Ryan
Harrisburg Bus Station
No tags
Next departures for Chicago to Harrisburg on December 14
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Downtown Greyhound Station
Harrisburg Bus Station
Cheapest
Bus
Downtown Greyhound Station
Harrisburg Bus Station
Fastest
Bus
Downtown Greyhound Station
Harrisburg Bus Station
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Downtown Greyhound Station
Harrisburg Bus Station
No tags
Bus
Chicago 95Th & Dan Ryan
Harrisburg Bus Station
No tags
Next departures for Chicago to Harrisburg on December 18
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Downtown Greyhound Station
Harrisburg Bus Station
Cheapest
Bus
Downtown Greyhound Station
Harrisburg Bus Station
Fastest
FlixBus + Greyhound Lines, Inc.
Bus
Downtown Greyhound Station
Harrisburg Bus Station
No tags
Bus
Downtown Greyhound Station
Harrisburg Bus Station
No tags
Bus
Downtown Greyhound Station
Harrisburg Bus Station
No tags
Last refresh of the prices: Yesterday at 3:14 AM CST.
Compare 2 ways to go from Chicago to Harrisburg
We recommend taking the bus
Among the sustainable travel choices, the bus stands out as the good way to reach Harrisburg. The journey takes about 17 hours and with fares starting at just $84, it presents an excellent value for a comfortable ride.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Greyhound Chicago Harrisburg recent customer reviews
I have had a very bad experience on my vacation due to your bus service
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Frequently asked questions about traveling from Chicago to Harrisburg by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Chicago to Harrisburg?
The cheapest bus tickets from Chicago to Harrisburg start from $84. The average price for this route is around $141. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Chicago to Harrisburg?
The average bus trip duration from Chicago to Harrisburg is 17h, covering a distance of 570 miles (920 km). The quickest bus can get you there in 15h 15m and is operated by Greyhound.
Which bus companies service the Chicago to Harrisburg route?
Several major bus companies operate on this route with 10 buses available per day, including services from Greyhound, FlixBus.
What is the earliest and latest departure time for the bus from Chicago to Harrisburg?
The earliest bus departs from Chicago to Harrisburg at 5:25am. And the latest bus departs at 11:40pm.
What are the CO₂ emissions for the bus trip from Chicago to Harrisburg?
A bus trip from Chicago to Harrisburg generates an estimated 23 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Chicago to Harrisburg?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87412 reviews.
Which bus company has the best Wi-Fi from Chicago to Harrisburg?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Chicago to Harrisburg?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Chicago to Harrisburg?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
12/10
$134
12/11
$155
Today
$154
12/13
$155
12/14
$98
12/15
No data
12/16
No data
12/17
No data
The cheapest trip from Chicago to Harrisburg was searched and found on Dec 14, 2025 with a price of $98
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Harrisburg, as early as possible.
You can expect to pay from $98 to $256 for a bus ticket from Chicago to Harrisburg based on the last 2 days. You can expect to find the cheapest price for the trip at $98 which is on 2025-12-14.
Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Chicago to Harrisburg?
The bus is the cheapest travel choice for this destination