Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Cincinnati Bus Station | Des Moines | Cheapest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Cincinnati Bus Station | Des Moines | Fastest |
Last refresh of the prices: Last Friday at 3:11 AM EST.
Get from Cincinnati to Des Moines
The journey takes about 18 hours 40 minutes, and with fares starting at just $132, it presents an excellent value for a comfortable ride.
Where are the popular stops in Cincinnati and Des Moines?
Stops in Cincinnati
- A1005 Gilbert Ave, Cincinnati, OH 45202
- B
Northland Blvd
290-322 Northland Blvd, Springdale, OH 45246, USA
Compare bus companies
Based on 87493 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $133
Frequently asked questions about travelling from Cincinnati to Des Moines by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Cincinnati to Des Moines?
The cheapest bus tickets from Cincinnati to Des Moines start from $132. The average price for this route is around $159. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Cincinnati to Des Moines?
The average bus travel time from Cincinnati to Des Moines is 18h 40m, covering a distance of 819 km. The quickest bus can get you there in 22h 5m and is operated by Greyhound.
Which bus companies service the Cincinnati to Des Moines route?
Several major bus companies operate on this route with 2 buses available per day.
What are the earliest and latest departure times for the bus from Cincinnati to Des Moines?
The earliest bus departs from Cincinnati to Des Moines at 12:55am. And the latest bus departs at 5:30pm.
What are the CO₂ emissions for the bus trip from Cincinnati to Des Moines?
A bus trip from Cincinnati to Des Moines generates an estimated 20 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Cincinnati to Des Moines was searched and found on Jan 13, 2026 with a price of $121To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Cincinnati to Des Moines, as early as possible.
You can expect to pay from $121 to $170 for a bus ticket from Cincinnati to Des Moines based on the last 2 days. You can expect to find the cheapest price for the trip at $121 which is on 2026-01-13.
