Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Des Moines | Spokane North | CheapestFastest | ||||
| Bus | Des Moines | Spokane North | No tags |
Last refresh of the prices: Last Monday at 5:42 AM CST.
Get from Des Moines to Spokane
The journey takes about 1 day, 12 hours 29 minutes, and with fares starting at just $275, it presents an excellent value for a comfortable ride.
Where are the popular stops in Des Moines and Spokane?
Stops in Des Moines
Stops in Spokane
- A9000 WEST AIRPORT DRIVE, 99224 Spokane, WA, USA
Compare bus companies
Based on 765 reviews, the company was rated 3.9 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Jefferson Lines ticket prices on this trip start at $275
Frequently asked questions about travelling from Des Moines to Spokane by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Des Moines to Spokane?
The cheapest bus tickets from Des Moines to Spokane start from $275. The average price for this route is around $275. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Des Moines to Spokane?
The average bus travel time from Des Moines to Spokane is 1d 12h, covering a distance of 1991 km. The quickest bus can get you there in 1d 8h and is operated by Jefferson Lines.
Which bus companies service the Des Moines to Spokane route?
Several major bus companies operate on this route with 2 buses available per day.
What are the earliest and latest departure times for the bus from Des Moines to Spokane?
The earliest bus departs from Des Moines to Spokane at 12:01am. And the latest bus departs at 6:50pm.
What are the CO₂ emissions for the bus trip from Des Moines to Spokane?
A bus trip from Des Moines to Spokane generates an estimated 50 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Des Moines to Spokane was searched and found on Jan 12, 2026 with a price of $268To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Des Moines to Spokane, as early as possible.
You can expect to pay from $268 to $275 for a bus ticket from Des Moines to Spokane based on the last 2 days. You can expect to find the cheapest price for the trip at $268 which is on 2026-01-15.
