How much is the bus ticket from Des Moines to Spokane?

The cheapest bus tickets from Des Moines to Spokane start from $193. The average price for this route is around $193. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Des Moines to Spokane?

The average bus trip duration from Des Moines to Spokane is 1d 12h, covering a distance of 1235 miles (1991 km). The quickest bus can get you there in 1d 8h and is operated by Jefferson Lines .

Which bus companies service the Des Moines to Spokane route?

Several major train operators operate on this route with 2 trains available per day.

What is the earliest and latest departure time for the bus from Des Moines to Spokane?

The earliest bus departs from Des Moines to Spokane at 12:01am. And the latest bus departs at 6:50pm.

What are the CO₂ emissions for the bus trip from Des Moines to Spokane?

A bus trip from Des Moines to Spokane generates an estimated 50 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

Bus Des Moines to Spokane from $188 | Refundable Tickets

Next bus departures

Next departures for Des Moines to Spokane on January 15
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Bus	3:45am	Des Moines	1d 8h	10:30am	Spokane North	CheapestFastest
	Bus	6:50pm	Des Moines	1d 17h	10:30am	Spokane North	No tags

Next departures for Des Moines to Spokane on January 16
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	3:45am	Des Moines	1d 8h	10:30am	Spokane North	CheapestFastest
Bus	12:01am	Des Moines	1d 12h	10:30am	Spokane North	No tags
Bus	6:50pm	Des Moines	1d 17h	10:30am	Spokane North	No tags

Next departures for Des Moines to Spokane on January 18
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	3:45am	Des Moines	1d 8h	10:30am	Spokane North	CheapestFastest
Bus	12:01am	Des Moines	1d 12h	10:30am	Spokane North	No tags
Bus	6:50pm	Des Moines	1d 17h	10:30am	Spokane North	No tags

Last refresh of the prices: Last Monday at 5:42 AM CST.

Get from Des Moines to Spokane

This route is served by bus only

The journey takes about 1 day, 12 hours 29 minutes and with fares starting at just $193, it presents an excellent value for a comfortable ride.

2bus per day

1d 12hAverage Duration

1235 milesDistance

50kgCO₂ emissions

Where are the popular stops in Des Moines and Spokane?

Stops in Des Moines

A
Jefferson/Trailways Depot
1501 2nd Ave North, Des Moines, IA 50314
Map
B
1514 East Grand Ave
1514 East Grand Avenue,, Des Moins, IA, 50316
Map

Stops in Spokane

A
Amtrak / Greyhound Station
9000 WEST AIRPORT DRIVE, 99224 Spokane, WA, USA
Visit page Map

Compare bus companies

Jefferson Lines

4/5765 reviews

Staff4.1

Timeliness3.6

Cleanliness4.4

Wifi2.5

Founded in 1919, Jefferson Lines provides bus services across the Midwest in the US. Their buses have WiFi, USB plugs, bathrooms, reclining seats, reading lights and GPS tracking. Tickets are non-refundable, but you can change the date by paying a fee. Known for their affordable prices and convenient schedules, if you're looking to travel in the Midwest, Jefferson Lines is the way to go.

US bus companies:FlixBus, BlaBlaCar Bus, Greyhound, ALSA, Intercape, Trenitalia, Big Sky

Frequently asked questions about traveling from Des Moines to Spokane by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Des Moines to Spokane?
The cheapest bus tickets from Des Moines to Spokane start from $193. The average price for this route is around $193. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Des Moines to Spokane?
The average bus trip duration from Des Moines to Spokane is 1d 12h, covering a distance of 1235 miles (1991 km). The quickest bus can get you there in 1d 8h and is operated by Jefferson Lines.
Which bus companies service the Des Moines to Spokane route?
Several major train operators operate on this route with 2 trains available per day.
What is the earliest and latest departure time for the bus from Des Moines to Spokane?
The earliest bus departs from Des Moines to Spokane at 12:01am. And the latest bus departs at 6:50pm.
What are the CO₂ emissions for the bus trip from Des Moines to Spokane?
A bus trip from Des Moines to Spokane generates an estimated 50 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

01/12

$188

01/13

$188

Today

$188

01/15

$188

01/16

$188

01/17

No data

01/18

$188

01/19

No data

The cheapest trip from Des Moines to Spokane was searched and found on Jan 12, 2026 with a price of $188

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Des Moines to Spokane, as early as possible.

You can expect to pay from $188 to $193 for a bus ticket from Des Moines to Spokane based on the last 2 days. You can expect to find the cheapest price for the trip at $188 which is on 2026-01-15.