Bus Tickets from Florence, SC to Buffalo, NY

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SatMay 10
SunMay 11
from US$185
MonMay 12
TueMay 13
WedMay 14
ThuMay 15
FriMay 16
SatMay 17

Cheap buses leaving Sunday

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: May 11 at
    Departure city: Florence
    Departure location: Florence, SC
    Arrival time: May 12 at
    Destination city: Buffalo
    Destination location: Niagara Frontier Transportation Authority
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: May 11 at
    Departure city: Florence
    Departure location: Florence, SC
    Arrival time: May 12 at
    Destination city: Buffalo
    Destination location: Buffalo (BUF) Airport
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: May 11 at
    Departure city: Florence
    Departure location: Florence, SC
    Arrival time: May 12 at
    Destination city: Buffalo
    Destination location: Buffalo (BUF) Airport
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:

Last refresh of the prices: Last Sunday at 1:47 PM EDT.

Prices and availability are subject to change.

Accepted payments

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Compare 2 ways to go from Florence to Buffalo

Bus
Average PriceUS$171 - US$323Average Duration1d
24kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average PriceUS$227 - US$484Average Duration22h 10m
88kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the train from Florence to Buffalo

Among the sustainable travel choices, the train stands out as a good way to reach Buffalo. The journey takes about 22 hours 10 minutes, and with fares starting at just US$227, it presents an excellent value for a comfortable ride.

3train per day
22h 10mAverage Duration
US$227Cheapest ticket
88kgCO₂ emissions

Bus Florence to Buffalo: Trip Overview

Average Ticket PriceUS$229
Average Bus Trip Duration1d
Number of daily buses2
Earliest bus departure5:35am
Distance969 km
Latest bus departure11:59pm

Florence to Buffalo Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Florence to Buffalo.

We make it our job to connect you with the most dependable bus companies that cover bus service from Florence to Buffalo.

Whether it is cheap bus tickets or more luxurious buses going to Buffalo from Florence, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Florence - Buffalo

  1. How long is the bus trip from Florence to Buffalo?

    The bus ride from Florence to Buffalo takes 1d, on average. If you're looking for the fastest way to get there, you'll find a bus doing the trip in about 22h 6m.

  2. How far is Florence from Buffalo?

    The distance covered from Florence to Buffalo is 969 km (601 miles).

  3. What are the departure and arrival locations for buses traveling from Florence to Buffalo?

    Buses traveling this route start their trip at Florence Bus Station, in Florence, and end it at Buffalo Airport, in Buffalo.

  4. What is the cheapest way to go from Florence to Buffalo?

    Taking the bus is the cheapest option to travel from Florence to Buffalo. Starting at US$171, this bus is the most cost-effective option for your journey.

  5. How much does it cost to take the bus from Florence to Buffalo?

    The bus fare from Florence to Buffalo is approximately US$229.

  6. Can I take an overnight bus from Florence to Buffalo?

    Yes! Catch buses leaving from Florence until 11:59pm and reaching Buffalo on the following day.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05-06
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05-07
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Today
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05-09
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05-10
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05-11
US$177
05-12
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05-13
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busbud logoThe cheapest trip from Florence to Buffalo was searched and found on May 11, 2025 with a price of US$177

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence to Buffalo, as early as possible.

You can expect to pay from US$177 to US$177 for a bus ticket from Florence to Buffalo based on the last 2 days. You can expect to find the cheapest price for the trip at US$177 which is on 2025-05-11.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Florence to Buffalo but it'll also be endearing to native speakers who will surely appreciate your effort.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Florence to Buffalo.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Florence to Buffalo.

Tune out to the fine sounds of your best music playlist on your bus trip from Florence to Buffalo while indulging in miles on end of beautiful scenic views.

Did you know?

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

What's the cheapest way to go from Florence to Buffalo?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Florence by bus?

Bus from Florence to Buffalo

You can also go to Buffalo by train

Train from Florence to Buffalo

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