Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | Bus station | Wilmington Bus Station | Cheapest | ||||
 | Bus | Florence, SC | Newark (DE) | Fastest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Florence, SC | Wilmington Bus Station | No tags | ||||
| Bus | Florence, SC | Delaware Rest Stop S | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Bus station | Wilmington Bus Station | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Bus station | Newark (DE) | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Bus station | Newark (DE) | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Bus station | Delaware Rest Stop S | No tags |
Last refresh of the prices: Yesterday at 7:40 PM EDT.
Compare 2 ways to go from Florence to Wilmington
Among the sustainable travel choices, the Bus stands out as a good way to reach Wilmington. The journey takes about 17 hours, and with fares starting at just CHF 52, it presents an excellent value for a comfortable ride.
Bus stations and stops in Florence and Wilmington
Stops in Florence
- A
Florence Bus Station
619 S Irby St, Florence, SC 29501, USA - B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA
Stops in Wilmington
- A
Wilmington Bus Station
Wilmington Bus Station, 101 N French St, Wilmington, DE 19801, USA - B
Amtrak/SEPTA Station
100 French St, Wilmington, DE 19801, USA - C
Wilmington Bus Stop
101 N French , Wilmington, DE 19801
Compare bus companies
Frequently asked questions about travelling from Florence, SC, US to Wilmington, DE by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Florence to Wilmington?
The cheapest bus tickets from Florence to Wilmington start from CHF 52. The average price for this route is around CHF 83. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Florence to Wilmington?
The average bus travel time from Florence to Wilmington is 17h, covering a distance of 714 km. The quickest bus can get you there in 12h 15m and is operated by FlixBus.
Which bus companies service the Florence to Wilmington route?
What are the earliest and latest departure times for the bus from Florence to Wilmington?
The earliest bus departs from Florence to Wilmington at 12:05am. And the latest bus departs at 7:20pm.
What are the CO₂ emissions for the bus trip from Florence to Wilmington?
A bus trip from Florence to Wilmington generates an estimated 17.826974999999997 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Florence to Wilmington?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 15390 reviews.
Which bus company has the best Wi-Fi from Florence to Wilmington?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Florence to Wilmington?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Florence to Wilmington?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Florence, SC, US to Wilmington, DE was searched and found on Aug 31, 2026 with a price of CHF 73To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Wilmington, DE, as early as possible.
You can expect to pay from CHF 73 to CHF 137 for a bus ticket from Florence, SC, US to Wilmington, DE based on the last 2 days. You can expect to find the cheapest price for the trip at CHF 73 which is on 2026-08-31.
What's the cheapest way to go from Florence, SC, US to Wilmington, DE?
The Bus is the cheapest travel choice for this destination
