Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | 2301 W Lucas St. | O'Donnell St. & Travel Plaza, Infront of TA Gas station | CheapestFastest | ||||
| Bus | 2301 W Lucas St. | O'Donnell St. & Travel Plaza, Infront of TA Gas station | No tags | ||||
 | Bus | Bus station | Baltimore Downtown Bus Station | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Bus station | Baltimore Bus Stop | No tags | ||||
 | Bus | Florence, SC | Baltimore Downtown Bus Station | No tags |
Last refresh of the prices: Yesterday at 1:20 PM EST.
Compare 2 ways to go from Florence to Baltimore
Among the sustainable travel choices, the bus stands out as a good way to reach Baltimore. The journey takes about 10 hours 15 minutes, and with fares starting at just $92, it presents an excellent value for a comfortable ride.
Where are the popular stops in Florence and Baltimore?
Stops in Florence
- A619 S Irby St, Florence, SC 29501, USA
- B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA
Stops in Baltimore
- A
Baltimore Downtown Bus Station
2110 Haines St, Baltimore, MD 21230, United States - B7 St Paul St, Baltimore, MD 21201, USA
- D1578 Maryland Ave, Baltimore, MD 21201, USA
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Frequently asked questions about travelling from Florence, SC, US to Baltimore by bus
What is the travel distance from Florence to Baltimore?
The distance between Florence and Baltimore is around 627 km (389 miles).
What are the departure and arrival locations for buses traveling from Florence to Baltimore?
Buses traveling this route start their trip at Florence Bus Station, in Florence, and end it at Baltimore Downtown Bus Station, in Baltimore.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Florence, SC, US to Baltimore was searched and found on Nov 26, 2025 with a price of $120To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Baltimore, as early as possible.
You can expect to pay from $120 to $347 for a bus ticket from Florence, SC, US to Baltimore based on the last 2 days. You can expect to find the cheapest price for the trip at $120 which is on 2025-11-26.
What's the cheapest way to go from Florence, SC, US to Baltimore?
The bus is the cheapest travel choice for this destination
