What is the travel distance from Florence to Baltimore?

The distance between Florence and Baltimore is around 627 km (389 miles).

What are the departure and arrival locations for buses traveling from Florence to Baltimore?

Buses traveling this route start their trip at Florence Bus Station, in Florence, and end it at Baltimore Downtown Bus Station, in Baltimore.

Bus Florence to Baltimore from $90 | Refundable Tickets

Next bus departures

Next departures for Florence to Baltimore on November 24
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	7:00pm	2301 W Lucas St.	8h 45m	3:45am	O'Donnell St. & Travel Plaza, Infront of TA Gas station	CheapestFastest
	Bus	9:00pm	2301 W Lucas St.	10h 15m	7:15am	O'Donnell St. & Travel Plaza, Infront of TA Gas station	No tags
	Bus	4:30pm	Bus station	11h 35m	4:05am	Baltimore Downtown Bus Station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	4:30pm	Bus station	15h 15m	7:45am	Baltimore Bus Stop	No tags
	Bus	12:05am	Florence, SC	9h 20m	9:25am	Baltimore Downtown Bus Station	No tags

Last refresh of the prices: Today at 1:20 PM EST.

Compare 2 ways to go from Florence to Baltimore

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach Baltimore. The journey takes about 10 hours 15 minutes, and with fares starting at just $92, it presents an excellent value for a comfortable ride.

5bus per day

10h 15mAverage Duration

631 kmDistance

16kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$92 - $215	Average Duration10h 15m	CO₂ emissions 16kg CO₂e
Train	Average Price$120 - $437	Average Duration9h 44m	CO₂ emissions 58kg CO₂e

Where are the popular stops in Florence and Baltimore?

Stops in Florence

A
Florence Bus Station
619 S Irby St, Florence, SC 29501, USA
Visit page
B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA

Stops in Baltimore

A
Baltimore Downtown Bus Station
2110 Haines St, Baltimore, MD 21230, United States
Visit page
B
Penn Station
7 St Paul St, Baltimore, MD 21201, USA
Visit page
C
Baltimore Airport
Visit page
D
Maryland Ave & I-83
1578 Maryland Ave, Baltimore, MD 21201, USA
Visit page

Compare bus companies

Wanda Coach

2.5/5649 reviews

Staff3

Timeliness2.8

Cleanliness2.4

Wifi1.7

Greyhound

3.5/587,392 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

FlixBus

3.5/511,414 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

US Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about travelling from Florence, SC, US to Baltimore by bus

What is the travel distance from Florence to Baltimore?
The distance between Florence and Baltimore is around 627 km (389 miles).
What are the departure and arrival locations for buses traveling from Florence to Baltimore?
Buses traveling this route start their trip at Florence Bus Station, in Florence, and end it at Baltimore Downtown Bus Station, in Baltimore.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11-21

$145

11-22

$138

Today

$145

11-24

$145

11-25

No data

11-26

$120

11-27

No data

11-28

No data

The cheapest trip from Florence, SC, US to Baltimore was searched and found on Nov 26, 2025 with a price of $120

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Baltimore, as early as possible.

You can expect to pay from $120 to $347 for a bus ticket from Florence, SC, US to Baltimore based on the last 2 days. You can expect to find the cheapest price for the trip at $120 which is on 2025-11-26.