Previously seen trips

Next departures for Florence to Wilmington on September 1
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location
FlixBus + Greyhound	Bus	12:05am	Florence, SC	16h 40m	4:45pm	Wilmington Bus Station
	Bus	12:05am	Florence, SC	12h 15m	12:20pm	Newark (DE)
FlixBus + Greyhound	Bus	4:15pm	Bus station	21h 15m	1:30pm	Delaware Rest Stop S
Greyhound + FlixBus	Bus	4:15pm	Bus station	13h 40m	5:55am	Wilmington Bus Station
Greyhound + FlixBus	Bus	4:15pm	Bus station	18h 45m	11:00am	Delaware Rest Stop S

Compare 2 ways to go from Florence to Wilmington

We recommend taking the bus

Among the sustainable travel choices, the Bus stands out as a good way to reach Wilmington. The journey takes about 17 hours and with fares starting at just PEN 217, it presents an excellent value for a comfortable ride.

7bus per day

17hAverage Duration

443 milesDistance

18kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average PricePEN 217 - PEN 784	Average Duration17h	CO₂ emissions 18kg CO₂e
Train	Average PricePEN 333 - PEN 1,283	Average Duration10h 32m	CO₂ emissions 66kg CO₂e

Bus stations and stops in Florence and Wilmington

Stops in Florence

A
Florence Bus Station
619 S Irby St, Florence, SC 29501, USA
Visit page
B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA

Stops in Wilmington

A
Wilmington Bus Station
Wilmington Bus Station, 101 N French St, Wilmington, DE 19801, USA
Visit page
B
Amtrak/SEPTA Station
100 French St, Wilmington, DE 19801, USA
Visit page
C
Wilmington Bus Stop
101 N French , Wilmington, DE 19801

Compare bus companies

FlixBus

3.5/515,456 reviews

Staff4.1

Timeliness4.0

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Greyhound

3.5/588,110 reviews

Staff3.6

Timeliness3.0

Cleanliness3.4

Wifi2.5

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies:FlixBus, Greyhound, Futura, Chihuahuenses, Tufesa, Adirondack Trailways, Valley Transit

Frequently asked questions about traveling from Florence, SC, US to Wilmington, DE by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Florence to Wilmington?
The cheapest bus tickets from Florence to Wilmington start from PEN 217. The average price for this route is around PEN 344. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Florence to Wilmington?
The average bus trip duration from Florence to Wilmington is 17h, covering a distance of 443 miles (714 km). The quickest bus can get you there in 12h 15m and is operated by FlixBus.
Which bus companies service the Florence to Wilmington route?
Several major bus companies operate on this route with 7 buses available per day, including services from FlixBus, Greyhound.
What is the earliest and latest departure time for the bus from Florence to Wilmington?
The earliest bus departs from Florence to Wilmington at 12:05am. And the latest bus departs at 7:20pm.
What are the CO₂ emissions for the bus trip from Florence to Wilmington?
A bus trip from Florence to Wilmington generates an estimated 17.826974999999997 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Florence to Wilmington?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 15443 reviews.
Which bus company has the best Wi-Fi from Florence to Wilmington?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Florence to Wilmington?
According to Busbud traveler reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Florence to Wilmington?
According to Busbud traveler reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

08/29

PEN 408

08/30

PEN 304

Today

PEN 302

09/01

PEN 408

09/02

No data

09/03

No data

09/04

No data

09/05

No data

The cheapest trip from Florence, SC, US to Wilmington, DE was searched and found on Aug 31, 2026 with a price of PEN 302

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Wilmington, DE, as early as possible.

You can expect to pay from PEN 302 to PEN 416 for a bus ticket from Florence, SC, US to Wilmington, DE based on the last 2 days. You can expect to find the cheapest price for the trip at PEN 408 which is on 2026-09-01.