Bus Tickets from Gainesville, FL to Port Saint Lucie

Next departures

Next departures for Gainesville to Port Saint Lucie on October 9
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus
Rosa Parks Station
Port St. Lucie (Park & Ride)Cheapest
FlixBus
Rosa Parks Station
Port St. Lucie (Park & Ride)Fastest
Greyhound Lines, Inc.
Gainesville Bus Stop
Port St. Lucie (Park & Ride)No tags

Last refresh of the prices: Yesterday at 6:25 PM EDT.

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Bus Gainesville, FL to Port Saint Lucie: Trip Overview

Average Ticket PriceUS$80
Average Bus Trip Duration9h 10m
Number of daily buses2
Earliest bus departure6:30am
Distance324 km
Latest bus departure9:20pm

Gainesville to Port Saint Lucie Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Gainesville to Port Saint Lucie.

We make sure you can find a bus service from Gainesville to Port Saint Lucie from the most reliable bus companies operating this trip.

Discover how much the bus trip from Gainesville to Port Saint Lucie will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Gainesville, FL - Port Saint Lucie

  1. What is the travel distance from Gainesville to Port Saint Lucie?

    The distance between Gainesville and Port Saint Lucie is around 326 km (203 miles).

  2. What are the departure and arrival locations for buses traveling from Gainesville to Port Saint Lucie?

    Buses traveling this route start their trip at Rosa Parks Station, in Gainesville, and end it at Port St Lucie Mobil Gas Bus Stop, in Port Saint Lucie.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10-06
US$77
10-07
US$77
Today
US$42
10-09
US$44
10-10
No data
10-11
No data
10-12
No data
10-13
No data
busbud logoThe cheapest trip from Gainesville, FL to Port Saint Lucie was searched and found on Oct 8, 2025 with a price of US$42

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Gainesville, FL to Port Saint Lucie, as early as possible.

You can expect to pay from US$42 to US$97 for a bus ticket from Gainesville, FL to Port Saint Lucie based on the last 2 days. You can expect to find the cheapest price for the trip at US$44 which is on 2025-10-09.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Gainesville to Port Saint Lucie but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Gainesville to Port Saint Lucie, get comfy and count the stars.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Gainesville to Port Saint Lucie will emit less CO2 than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from Gainesville to Port Saint Lucie while indulging in miles on end of beautiful scenic views.

Did you know?

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Will you be returning to Gainesville, FL by bus?

Bus from Port Saint Lucie to Gainesville, FL

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