Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Rosa Parks Station | Port St. Lucie (Park & Ride) | Cheapest | ||||
| Bus | Rosa Parks Station | Port St. Lucie (Park & Ride) | Fastest | ||||
 | Bus | Gainesville Bus Stop | Port St. Lucie (Park & Ride) | No tags |
Last refresh of the prices: Yesterday at 23:33 EST.
Get from Gainesville to Port Saint Lucie
The journey takes about 9 hours 10 minutes, and with fares starting at just £63, it presents an excellent value for a comfortable ride.
Where are the popular stops in Gainesville and Port Saint Lucie?
Stops in Gainesville
- A700 SE 3rd St, Gainesville, FL 32601
- B3509 SW Williston Rd, Gainesville, FL 32608, USA
- C101 NE 23rd Ave, Gainesville, FL 32609
Stops in Port Saint Lucie
- A
Port St Lucie Mobil Gas Bus Stop
1820 Sw Fountainview Blvd, Port Saint Lucie, FL 34986 - B
Port Saint Lucie - Wendys
1790 SW St Lucie W Blvd, Port St Lucie, FL 34986 - C
Port Saint LucieService Plaza
Florida's Turnpike, Milepost 144, Port St Lucie, FL 34984, USA - D
Port Saint Lucie Bus Stop
2198 SW Gatlin Blvd. Port St. Lucie, FL 34953
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Frequently asked questions about travelling by bus from Gainesville, FL to Port Saint Lucie
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Gainesville to Port Saint Lucie?
The cheapest coach tickets from Gainesville to Port Saint Lucie start from £63. The average price for this route is around £79. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Gainesville to Port Saint Lucie?
The average bus journey time from Gainesville to Port Saint Lucie is 9h 10m, covering a distance of 201 miles. The fastest bus can take you there in 5h 55m and is operated by FlixBus.
Which bus companies service the Gainesville to Port Saint Lucie route?
What is the earliest and latest departure time for the bus from Gainesville to Port Saint Lucie?
The earliest bus departs from Gainesville to Port Saint Lucie at 05:30. And the latest bus departs at 21:20.
What are the CO₂ emissions for the bus trip from Gainesville to Port Saint Lucie?
A bus journey from Gainesville to Port Saint Lucie produces an estimated 8 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Which is the best bus company from Gainesville to Port Saint Lucie?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11380 reviews.
Which company has the best Wi-Fi from Gainesville to Port Saint Lucie?
Based on Busbud reviews, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from Gainesville to Port Saint Lucie?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Gainesville to Port Saint Lucie?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Gainesville, FL to Port Saint Lucie was searched and found on 2 Dec 2025 with a price of £66To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Gainesville, FL to Port Saint Lucie as early as possible.
You can expect to pay from £66 to £146 for a bus ticket from Gainesville, FL to Port Saint Lucie based on the last 2 days. You can expect to find the cheapest price for the trip at £66, which is on 2025-12-02.
Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
