How much is the bus ticket from Gainesville to Port Saint Lucie?

The cheapest bus tickets from Gainesville to Port Saint Lucie start from $81. The average price for this route is around $102. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Gainesville to Port Saint Lucie?

The average bus trip duration from Gainesville to Port Saint Lucie is 9h 10m, covering a distance of 201 miles (324 km). The quickest bus can get you there in 5h 55m and is operated by FlixBus .

Which bus companies service the Gainesville to Port Saint Lucie route?

Several major bus companies operate on this route with 2 buses available per day, including services from FlixBus , Greyhound .

What is the earliest and latest departure time for the bus from Gainesville to Port Saint Lucie?

The earliest bus departs from Gainesville to Port Saint Lucie at 5:30am. And the latest bus departs at 9:20pm.

What are the CO₂ emissions for the bus trip from Gainesville to Port Saint Lucie?

A bus trip from Gainesville to Port Saint Lucie generates an estimated 8 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

What is the best bus company from Gainesville to Port Saint Lucie?

According to Busbud customers, the highest-rated bus company on this route is FlixBus , with an average rating of 3.5 out of 5 stars based on 11380 reviews.

Which bus company has the best Wi-Fi from Gainesville to Port Saint Lucie?

Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

Which bus company has the most timely service from Gainesville to Port Saint Lucie?

According to Busbud traveller reviews, the most timely bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from Gainesville to Port Saint Lucie?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus , with a cleanliness rating of 4.1 out of 5 stars.

Bus Gainesville to Port Saint Lucie from $84 | Refundable Tickets

Next bus departures

Next departures for Gainesville to Port Saint Lucie on November 27
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Bus	9:20pm	Rosa Parks Station	5h 55m	3:15am	Port St. Lucie (Park & Ride)	CheapestFastest

Next departures for Gainesville to Port Saint Lucie on November 30
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	3:00pm	Rosa Parks Station	10h 35m	1:35am	Port St. Lucie (Park & Ride)	Cheapest
Bus	9:20pm	Rosa Parks Station	5h 55m	3:15am	Port St. Lucie (Park & Ride)	Fastest
Bus	6:30am	Gainesville Bus Stop	9h 10m	3:40pm	Port St. Lucie (Park & Ride)	No tags

Last refresh of the prices: Yesterday at 11:33 PM EST.

Get from Gainesville to Port Saint Lucie

This route is served by bus only

The journey takes about 9 hours 10 minutes and with fares starting at just $81, it presents an excellent value for a comfortable ride.

2bus per day

9h 10mAverage Duration

201 milesDistance

8kgCO₂ emissions

Where are the popular stops in Gainesville and Port Saint Lucie?

Stops in Gainesville

A
Rosa Parks Station
700 SE 3rd St, Gainesville, FL 32601
Visit page
B
Williston Rd & I-75
3509 SW Williston Rd, Gainesville, FL 32608, USA
Visit page
C
Greyhound Station
101 NE 23rd Ave, Gainesville, FL 32609
Visit page

Stops in Port Saint Lucie

A
Port St Lucie Mobil Gas Bus Stop
1820 Sw Fountainview Blvd, Port Saint Lucie, FL 34986
Visit page
B
Port Saint Lucie - Wendys
1790 SW St Lucie W Blvd, Port St Lucie, FL 34986
C
Port Saint LucieService Plaza
Florida's Turnpike, Milepost 144, Port St Lucie, FL 34984, USA
D
Port Saint Lucie Bus Stop
2198 SW Gatlin Blvd. Port St. Lucie, FL 34953

Compare bus companies

FlixBus

3.5/511,456 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Greyhound

3.5/587,402 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about traveling from Gainesville, FL to Port Saint Lucie by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Gainesville to Port Saint Lucie?
The cheapest bus tickets from Gainesville to Port Saint Lucie start from $81. The average price for this route is around $102. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Gainesville to Port Saint Lucie?
The average bus trip duration from Gainesville to Port Saint Lucie is 9h 10m, covering a distance of 201 miles (324 km). The quickest bus can get you there in 5h 55m and is operated by FlixBus.
Which bus companies service the Gainesville to Port Saint Lucie route?
Several major bus companies operate on this route with 2 buses available per day, including services from FlixBus, Greyhound.
What is the earliest and latest departure time for the bus from Gainesville to Port Saint Lucie?
The earliest bus departs from Gainesville to Port Saint Lucie at 5:30am. And the latest bus departs at 9:20pm.
What are the CO₂ emissions for the bus trip from Gainesville to Port Saint Lucie?
A bus trip from Gainesville to Port Saint Lucie generates an estimated 8 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Gainesville to Port Saint Lucie?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11380 reviews.
Which bus company has the best Wi-Fi from Gainesville to Port Saint Lucie?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Gainesville to Port Saint Lucie?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Gainesville to Port Saint Lucie?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/25

$123

11/26

$94

Today

$106

11/28

No data

11/29

No data

11/30

$115

12/01

No data

12/02

$84

The cheapest trip from Gainesville, FL to Port Saint Lucie was searched and found on Dec 2, 2025 with a price of $84

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Gainesville, FL to Port Saint Lucie, as early as possible.

You can expect to pay from $84 to $188 for a bus ticket from Gainesville, FL to Port Saint Lucie based on the last 2 days. You can expect to find the cheapest price for the trip at $84 which is on 2025-12-02.

Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.